摘要
Feed efficiency is one of the economically important traits for the cattle industry that affects profit (feed costs) and the environment (production of manure and methane). Due to that feed efficiency is driven by multi-factors, mechanisms contributing to the animal to animal variation in this trait have not been well defined, limiting the development of precision feeding strategies to improve the herd production efficiency. Rumen microbial fermentation and volatile fatty acids (VFA) production have been recently reported to be associated with cattle feed efficiency, however the roles of rumen epithelial function in feed efficiency are less studied although the rumen epithelium has an important function in VFA absorption and metabolism which can affect host feed efficiency. Rumen epithelium is colonized with a diverse microbial population, termed epimural microbiota, which has proposed functions in tissue development, barrier and inflammation, urea transport, and oxygen scavenging, suggesting that they can affect rumen epithelial functions and subsequently cattle feed efficiency. Especially, prospective functions of epimural microbiota, enhanced rumen immunity and increased rumen epithelial thickness, might contribute to less nutritional requirement for tissue recuperation. Thus, the understanding of the functions of rumen epithelium, epimural microbiota, and rumen epithelial host-microbe interactions is essential to identify their roles in contributing to feed efficiency. In this review, we will focus on to date research findings on the structure of rumen epithelium, epimural microbiota, and epithelial host-microbe interactions together with their functions and how these are associated with feed efficiency, aiming to provide insights on future directions to study rumen epithelial host-microbe interactions and improve the rumen functions in cattle.
摘要译文
饲料效率是影响利润（饲料成本）和环境（粪便和甲烷的生产）的养牛行业的经济特征之一。由于饲料效率是由多因素驱动的，因此在该特征中有助于动物变异的机制尚未得到很好的定义，从而限制了精确喂养策略的发展，以提高牛群生产效率。最近据报道，瘤胃微生物发酵和挥发性脂肪酸（VFA）的产生与牛的饲料效率有关，但是瘤胃上皮功能在饲料效率中的作用较少，尽管瘤胃上皮在VFA吸收和代谢中具有重要功能可以影响宿主饲料效率。瘤胃上皮在多种微生物种群定殖，称为表皮微生物群，它提出了在组织发育，屏障和炎症，尿素运输和氧气清除方面的功能，表明它们可以影响瘤胃上皮功能以及随后的牛喂养效率。特别是，表皮微生物群的前瞻性功能，增强的瘤胃免疫力和瘤胃上皮厚度的增加可能会导致组织恢复的营养需求减少。因此，对瘤胃上皮，表皮微生物群和瘤胃上皮宿主菌相互作用的功能的理解对于确定它们在促进饲料效率方面的作用至关重要。在这篇综述中，我们将重点介绍迄今为止有关瘤胃上皮，表皮微生物群和上皮宿主微杆相互作用的结构的研究结果，以及它们的功能以及它们如何与饲料效率相关联，旨在提供有关研究未来研究的见解。瘤胃上皮宿主 - 微叶相互作用并改善牛的瘤胃功能。
Sang Weon Na;Le Luo Guan. Understanding the role of rumen epithelial host-microbe interactions in cattle feed efficiency[J]. Animal Nutrition, 2022,10: 41-53