摘要
Oxidative stress defines a condition in which the prooxidant–antioxidant balance in the cell is disturbed, resulting in DNA hydroxylation, protein denaturation, lipid peroxidation, and apoptosis, ultimately compromising cells’ viability. Probiotics have been known for many beneficial health effects, and the consumption of probiotics alone or in food shows that strain-specific probiotics can present antioxidant activity and reduce damages caused by oxidation. However, the oxidation-resistant ability of probiotics, especially the underling mechanisms, is not properly understood. In this view, there is interest to figure out the antioxidant property of probiotics and summarize the mode of action of probiotic bacteria in antioxidation. Therefore, in the present paper, the antioxidant mechanisms of probiotics have been reviewed in terms of their ability to improve the antioxidant system and their ability to decrease radical generation. Since in recent years, oxidative stress has been associated with an altered gut microbiota, the effects of probiotics on intestinal flora composition are also elaborated.
摘要译文
氧化应激定义了细胞中促氧化抗氧化平衡的病症，导致DNA羟化，蛋白质变性，脂质过氧化和凋亡，最终损害细胞的活力。益生菌已知对于许多有益的健康影响，单独或食物中的益生菌消耗表明，菌株特异性益生菌可以呈现抗氧化活性并减少氧化引起的损伤。然而，益生菌抗氧化能力，尤其是损害机制，尚未正确理解。在这种观点中，有兴趣弄清楚益生菌的抗氧化性能，并总结益生菌在抗氧化中的作用方式。因此，在本文中，益生菌的抗氧化机制已经在改善抗氧化系统的能力和减少自由基产生的能力方面进行了审查。从近年来，氧化应激已经与肠道微生物生物改变有关，还阐述了益生菌对肠菌群组合物的影响。
Yang Wang; Yanping Wu; Yuanyuan Wang; Han Xu; Xiaoqiang Mei; Dongyou Yu; Yibing Wang[ [*];Weifen Li[ [*]. Antioxidant Properties of Probiotic Bacteria[J]. Nutrients, 2017,9(5): 521