摘要
Cancer treatments in veterinary medicine continue to evolve beyond the established standard therapies of surgery, chemotherapy and radiation therapy. New technologies in cancer therapy include a targeted mechanism to open the cell membrane based on electroporation, driving therapeutic agents, such as chemotherapy (electro-chemotherapy), for local control of cancer, or delivery of gene-based products (electro-gene therapy), directly into the cancer cell to achieve systemic control. This review examines electrochemotherapy and electro-gene therapy in veterinary medicine and considers future directions and applications.
摘要译文
兽医医学中的癌症治疗不断发展，超出了手术，化疗和放射治疗的既定标准疗法。癌症治疗中的新技术包括基于电穿孔打开细胞膜的靶向机制，驱动治疗药物（如化学疗法），用于局部控制癌症，或者将基因产物（电基因治疗）直接递送到癌细胞中以实现系统的控制。本综述检查了兽药中的电化疗和电疗法，并考虑了未来的方向和应用
J. Impellizeri[a]; L. Aurisicchio[b]; P. Forde[c]; D.M. Soden[c]. Electroporation in veterinary oncology[J]. The Veterinary Journal, 2016,217: 18–25