摘要
The aim of the present study was to analyze clinical and laboratory findings regarding goats submitted to the incorporation of monensin in their feed and assess its effects on the prevention of experimentally induced ruminal lactic acid. Clinical aspects as well as physiochemical and microbiological characteristics of the ruminal fluid were assessed. Twenty clinically healthy, castrated, male, mixed-breed goats with a mean weight of 30kg were used, in which permanent ruminal cannulae were implanted. Two groups of ten animals were formed: A control group (CG) and a group that received 33mg/kg of monensin (GM) per animal in the diet for 40 days. Ruminal acidosis was induced by administering 10g of sucrose/ kg of live weight, prior to the morning meal. Clinical observations and the collection of ruminal fluid were carried out at 4, 8, 12, 24, 32, 48 and 72h post-induction (PI). At 4 hours PI, there were signs of apathy, capricious appetite or anorexia, tachycardia, tachypnea, rumen stasis, abdominal distention and diarrhea of varying severity. The reflux of rumen fluid through the nostrils, signs of colic intestinal and serous bilateral nasal discharge was observed in some animals of the CG, and laminitis in GM. There was an average loss of body weight of 900g in CG (P>0.05) and 1.3kg in GM (P<0.05). There was a significant decrease (P<0.05) rumen pH falls below six; uptime sedimentation and flotation, viability, motility and density of protozoan, as of four hours of induction in GC and four to 24 hours in GM, the number of infusers, at 4 PI, both in CG and GM, which remained until the end of 72 hours, and the values of acetic, propionic and butyric acids in GM. The values of butyric acid in the GC reduced there is not significant difference (P>0.05). The color of the rumen fluid became milky, acid smell and watery consistency. There was a significant increase (P <0.05) the acidity, of the test time reduction of methylene blue, the values of chloride and lactic acid. The dynamics of the fauna and flora has changed, with a predominance of Grampositive. In some animals there was no full restoration of all variables. The use of monensin did not prevent the onset of the disorder fermentation in animals that received
摘要译文
分析关于山羊的临床和实验室结果，提交将莫能菌素并入饲料中，并评估其对预防实验诱导的瘤胃乳酸的作用评估了临床方面以及瘤胃液的生理化学和微生物学特征。二十临床健康，阉割，男性，使用平均体重30kg的混合品种山羊，其中植入永久性瘤胃插管形成两组10只动物：对照组（CG）和在饲料中每只动物接受33mg / kg莫能菌素（GM）40天的组在早餐前，通过施用10g蔗糖/ kg活体重来诱导瘤胃酸中毒。临床观察和在4,8,12,24和30分钟进行瘤胃液的收集。诱导后（PI）32,48和72小时。在4小时PI时，存在冷漠，反复性食欲或厌食，心动过速，呼吸急促，瘤胃停滞，腹胀和不同程度腹泻腹泻通过鼻孔，在CG的一些动物中观察到肠绞痛性和浆液性双侧鼻腔出血的迹象，并且GM 中的蹄叶炎在CG中平均体重损失900g（P0 和1 3kg在GM中（P 0）。显着降低（P 0，瘤胃pH下降到6以下;正常时间沉降和浮选，原生动物的活力和密度，在GC中诱导4小时，在GM中4至24小时，在CG和GM中的4 PI下的输注次数，其保持直到72小时结束，并且乙酸，丙酸和丁酸在GC中的含量丁酸在GC中的降低没有显着性差异（P0 ），瘤胃液的颜色变成乳白色，酸味和水稠度有显着增加（P 0。酸性，亚甲基蓝的测试时间减少，氯化物和乳酸的值动物和植物的动力学发生了变化，主要是Grampositive 在一些动物没有所有变量的完全恢复莫能菌素的使用没有防止接受的动物中的病症发酵的发生
MIR;A NETO, Eldinê G. de et al.. Clinical aspects and ruminal chemistry in goats with lactic acidosis and sodic monensin supplementation.[J]. Pesquisa Veterinária Brasileira, 2011,31(5): 416-424