摘要
Superovulation with intrauterine insemination (SO-IUI) has been suggested as an alternative to gamete intrafallopian transfer (GIFT), despite the absence of controlled or comparative trials. We retrospectively analyzed all GIFT and SO-IUI cycles performed concurrently from January 1985 to August of 1987 at a single university center. Pregnancy rates were significantly better for GIFT than SO-IUI (P<0.001), with an odds ratio of 3.25 (P=0.001). Stepwise multiple logistic regression identifield factors that correlate with pregnancy: absence of endometriosis (P=0.05), infertility<3 years' duration (P=0.002), TMS ≧30×106 (P=0.005), and treatment with GIFT rather than SO-IUI (P=0.001). These data give a first approximation of the increased efficacy of GIFT versus SO-IUI and provide valuable insight into significant confounding variables to be considered when planning a randomized, prospective trial to evaluate these techniques. Key Wordsgamete intrafallopian transfer (GIFT) superovulation intrauterine insemination
摘要译文
超数排卵与宫腔内人工授精(SO-IUI)已被建议作为一种替代配子输卵管内转移(GIFT),尽管不存在的控制或比较试验我们回顾性分析从1985年1月在一所大学中心同时进行至1987年8月所有的礼物,SO-IUI周期怀孕率分别为GIFT显著优于SO-IUI(P 0),用3(P \x3d 0)的比值比多元逐步回归identifield因素与怀孕相关:没有子宫内膜异位症(P \x3d 0,不孕3年的时间(P \x3d 0),TMS铌SUP 6 / SUP(P \x3d 0) ,和礼物,而不是SO-IUI(P \x3d 0)治疗这些数据尚礼的功效增加的第一个近似与SO-IUI,并提供有价值的见解显著混杂变量规划随机时必须考虑,前瞻性试验,以评估这些技术主要Wordsgamete输卵管内移植(GIFT)超数排卵宫腔内人工授精
Carolyn R. Kaplan [1] David L. Olive [1] Vincente Sabella [1] Ricardo H. Asch [1] Jose P. Balmaceda [1] Robert M. Riehl [1] Terry R. Groff [1] William N. Burns [1] Robert S. Schenken [1]. Gamete intrafallopian transfer vs superovulation with intrauterine insemination for the treatment of infertility[J]. Journal of Assisted Reproduction and Genetics, 1989,6(5): 298-304