摘要
Baculoviruses are invertebrate-specific pathogens which have been used as alternatives to chemical agents for the control of some insect pests. They have a large, double-stranded, circular DNA genome (ca. 80–200 kilobase pairs). This is packaged within a rod-shaped nucleocapsid structure, further enclosed within a lipoprotein envelope and ultimately occluded by a crystalline matrix largely comprising a single protein, polyhedrin (28 Kdal), which serves to protect the virus in the environment (Figure 1). In general, baculoviruses infect the larval stage in insect development and cause significant mortality and morbidity.
摘要译文
杆状病毒是无脊椎动物特异性病原体，已被用作控制某些害虫的化学试剂的替代物。它们具有大的双链环状DNA基因组（约80-200千碱基对）。将其包装在棒状核衣壳结构内，进一步包裹在脂蛋白包膜内，最终被结晶基质封闭，该结晶基质主要包含单一蛋白质，多角体蛋白（28Kdal），其用于保护环境中的病毒（图1）。通常，杆状病毒感染昆虫发育中的幼虫阶段并导致显着的死亡率和发病率。
Robert D. Possee[1];Linda A. King[2];Matthew D. Weitzman[2];Susan G. Mann[2];David S. Hughes[2];Iain R. Cameron[1];Mark L. Hirst[1];David H. L. Bishop[1]. Progress in the Genetic Modification and Field-Release of Baculovirus Insecticides. The Release of Genetically Modified Microorganisms—REGEM 2[M].DE: Springer, 1992: 47-58