摘要
The outbreak of deadly hantavirus pulmonary syndrome (HPS) in the United States in 1993 (CDC., 1993) changed the concept of hemorrhagic fever with renal syndrome (HFRS) (WHO, 1983) because the clinical manifestations of this newly described hantavirus infection (Duchin et al., 1994) are quite different from the known typical forms of HFRS caused by Hantaan, Seoul, and Puumala viruses and because it occurred in the United States, where hantavirus disease had not been known to exist previously. Recent data on hantavirus disease show that HFRS occurs in the Old World and HPS, caused by novel hantaviruses, occurs in the New World. Epidemiological studies of HFRS progressed rapidly after the discovery of Hantaan virus, the etiologic agent of Korean hemorrhagic fever (Lee and Lee, 1976; Lee et al., 1978) through seroepidemiologic surveys of hantavirus infections in humans and in animals. It was long believed that HFRS only occurs in certain limited rural areas of Eurasia, such as Korea, China, Far East of Russia, and Northern Europe (Lee, 1982). Recent findings (Lee and van der Groen, 1989; Lee et al., 1990b), however, have shown that HFRS patients can be found not only in rural areas but also in urban cities in many parts of the world.
摘要译文
1993年在美国爆发致命的汉坦病毒肺综合征（HPS）（CDC。，1993）改变了肾综合征出血热（HFRS）的概念（WHO，1983），因为这种新描述的汉坦病毒感染的临床表现（ Duchin等人，1994）与汉坦，首尔和普马拉病毒引起的HFRS的已知典型形式完全不同，并且因为它发生在美国，其中先前不知道汉坦病毒病。最近有关汉坦病毒病的数据表明，HFRS发生在旧世界，由新型汉坦病毒引起的HPS发生在新世界。 HFRS的流行病学研究在韩国出血热的病原体汉坦病毒的发现后迅速发展（Lee和Lee，1976; Lee等人，1978）通过对人类和动物中汉坦病毒感染的血清流行病学调查。人们一直认为，HFRS只发生在欧亚大陆的某些有限的农村地区，如韩国，中国，俄罗斯远东和北欧（Lee，1982）。最近的研究结果（Lee和van der Groen，1989;然而，Lee等人，1990b）已经表明，HFRS患者不仅可以在农村地区找到，而且可以在世界许多地方的城市中找到。
Ho Wang Lee[1]. Epidemiology and Pathogenesis of Hemorrhagic Fever with Renal Syndrome. The Bunyaviridae[M].DE: Springer, 1996: 253-267