图书章节

Androgen Receptor Distribution in the Testis 收藏

雄激素受体在睾丸中的分布

原文求助发布源

作者

C. A. Suarez-Quian;B. O. Oke;W. Vornberger;G. Prins;S. Xiao;N. A. Musto

关键词

Germ Cell ;Androgen Receptor ;Sertoli Cell ;Leydig Cell ;Seminiferous Epithelium

关键词译文

生殖细胞;雄激素受体;支持细胞; Leydig细胞;生精上皮细胞

页码

189-212

DOI

10.1007/978-1-4612-2374-0_13

来源信息

Cellular and Molecular Regulation of Testicular Cells ISBN：9781461275190, 1996年, 189-212页

摘要

Germ cells contain androgen receptor (AR). Germ cells do not contain androgen receptor. These diametrically opposed views are at the center of a long-running dispute regarding the cell site of androgen action within the testis (reviewed in 1, 2). In this chapter we examine AR distribution in the rat and mouse testis using an affinity-purified rabbit polyclonal antibody made to a 21 amino acid peptide of the amino terminus of the rat AR (3–5). Results reveal the presence of AR in testicular somatic cells, as well as in elongated spermatids.

摘要译文

生殖细胞含有雄激素受体（AR）。生殖细胞不含雄激素受体。这些截然相反的观点是关于睾丸内雄激素作用的细胞位点的长期争议的中心（在1,2中回顾）。在本章中，我们使用亲和纯化的兔多克隆抗体检测大鼠和小鼠睾丸中的AR分布，所述兔多克隆抗体制备于大鼠AR的氨基末端的21个氨基酸的肽（3-5）。结果显示在睾丸体细胞以及伸长的精子细胞中存在AR。

C. A. Suarez-Quian;B. O. Oke;W. Vornberger;G. Prins;S. Xiao;N. A. Musto. Androgen Receptor Distribution in the Testis. Cellular and Molecular Regulation of Testicular Cells[M].DE: Springer, 1996: 189-212