图书章节

Respiratory Hantaan Virus 收藏

呼吸性汉坦病毒
摘要
Hantaviruses were first recognized as a cause of serious disease in 1951 when 3000 United Nations troops in Korea developed an illness characterized by fever, headache, back and abdominal pain, with haemorrhage in many cases. This disease had a case-fatality of 5–10% and was named Korean haemorrhagic fever [18]. The causative agent was, putatively, termed ‘Hantaan’ after the river that now divides North and South Korea. Examination of historical records would, however, suggest that the illness has been recognized in many parts of the world for decades [4], if not centuries [37]. The disease course is characterized by increased capillary permeability and acute shock, resulting in renal failure. The term ‘haemorrhagic fever with renal syndrome (HFRS)’ has now been adopted to describe the illness.
摘要译文
汉坦病毒在1951年首次被认为是导致严重疾病的原因,当时韩国有3000名联合国军队患上了以发烧,头痛,背部和腹部疼痛为特征的疾病,许多病例都有出血。该病的病死率为5-10%,被称为韩国出血热[18]。在河流现在划分朝鲜和韩国之后,致使特工被称为“汉坦”。然而,对历史记录的检查表明,这种疾病已经在世界许多地方被认识了数十年[4],如果不是几个世纪[37]。疾病过程的特征是毛细血管通透性增加和急性休克,导致肾功能衰竭。现在已采用术语“肾综合征出血热(HFRS)”来描述这种疾病。
Steven Myint. Respiratory Hantaan Virus. Viral and Other Infections of the Human Respiratory Tract[M].DE: Springer, 1996: 309-317