摘要
Investigation of the biological activity of viruses in vitro necessitates some means of identifying their presence within cells and assaying their activity. Since virus particles themselves are metabolically inert, their detection and quantitation is dependent on their cellular effects or on synthesis of viral antigens, enzymes, and the like. Virus-induced cell fusion is a cytopathic cellular response easily recognizable by microscopic examination, which has been exploited to considerable advantage in virology, as will be briefly discussed.
摘要译文
在体外研究病毒的生物活性需要一些方法来鉴定它们在细胞内的存在并测定它们的活性。由于病毒颗粒本身是代谢惰性的，它们的检测和定量取决于它们的细胞效应或病毒抗原，酶等的合成。病毒诱导的细胞融合是通过显微镜检查容易识别的细胞病变细胞反应，已经在病毒学中被利用到相当大的优势，如将简要讨论的。
Myra O. McClure[1]. Syncytial Assays. Practical Molecular Virology[M].DE: Springer, 1992: 81-88