摘要
A 7-month-old male domestic ferret (Mustela putorius furo) was presented for evaluation of unilateral testicular enlargement. Microscopic examination of the left testicle revealed a neoplasm with differentiation along multiple cell lines (ectoderm, endoderm, mesoderm) including respiratory epithelium, bone and haired skin. A poorly differentiated epithelial component was dispersed throughout the neoplasm with invasion of testicular lymphatics. The animal developed progressive dysuria and was euthanized. At necropsy, metastasis of the poorly differentiated epithelial component was present in the urinary bladder, ureters, prostate gland, pelvic fat, abdominal and thoracic lymph nodes, kidney and lung. This is the first report of a malignant testicular teratoma with widespread metastasis in this species.
摘要译文
提出了一个7个月大的雄性雪貂（Mustela putorius furo），用于评估单侧睾丸增大。显微镜下检查左睾丸，发现肿瘤沿多个细胞系（外胚层，内胚层，中胚层）分化，包括呼吸道上皮，骨骼和毛发皮肤。分化较差的上皮成分散布在整个肿瘤中，并侵犯了睾丸淋巴管。动物发展为进行性排尿困难，并被安乐死。尸检时，膀胱，输尿管，前列腺，盆腔脂肪，腹部和胸腔淋巴结，肾和肺中存在分化差的上皮成分的转移。这是该物种中广泛转移的恶性睾丸畸胎瘤的首次报道。
Kelsey R.Fiddes[∗];JerryMurray[†];Bruce H.Williams[∗]. Testicular Teratocarcinoma in a Ferret (Mustela putorius furo)[J]. Journal of Comparative Pathology, 2020,181: 63-67