摘要
One hundred one years have passed since Metchnikoff made his first scientific contribution to probiotics study. Intestinal lactic acid bacteria (LAB) for humans are closely associated with the host's health because LAB is an important biodefense factor in preventing colonization and subsequent proliferation of pathogenic bacteria in the intestine. A probiotic is recently defined as "live microorganisms that when administered in adequate amount confer a health benefit on the host". Some species of LAB have been claimed as probiotics, such as Lactobacillus acidophilus, L. casei, L. fermentum, L. plantarum, L. reuteri, and Lactococcus lactis. For understanding the general mechanism of probiotics, this paper would explore the early studies relating to probiotics and intestinal microbiota, and briefly introduce the Prolongation of Life written by Elie Metctmikoff.
摘要译文
自Metchnikoff对益生菌的研究做出第一个科学贡献以来，已经过去了一百一年。人类肠道乳酸菌（LAB）与宿主的健康密切相关，因为乳酸菌是防止肠道病原菌定殖和随后繁殖的重要生物防御因子。益生菌最近被定义为活的微生物，当以足够的量给药时，它们可以为宿主带来健康益处。 LAB的某些物种已被称为益生菌，例如嗜酸乳杆菌，干酪乳杆菌，发酵乳杆菌，植物乳杆菌，路透氏乳杆菌和乳酸乳球菌。为了理解益生菌的一般机理，本文将探索与益生菌和肠道菌群有关的早期研究，并简要介绍Elie Metctmikoff撰写的《延长生命》。
Oh; Se-Jong;. Probiotics and Prolongation of Life[J]. Journal of Milk Science and Biotechnology 한국유가공학회지, 2008,26(2): 31-37