摘要
Vestibular signs are rarely reported in ferrets. This report documents the successful diagnosis and management of an otitis interna without otitis media in a ferret. A 4-year-old deslorelin-implanted female ferret presented with an acute-onset, 2-day history of circling and falling to the right, and a diminished appetite. Neurologic examination revealed a right-sided head tilt associated with bilateral horizontal nystagmus, which had a fast phase to the left. These findings strongly suggested a right-sided vestibular syndrome. A complete blood cell count, serum biochemistry panel, and CT scan were unremarkable. A 1.5T contrast-enhanced magnetic resonance imaging scan of the brain showed a hypointense T2 signal abnormality of the right inner ear, without the involvement of the middle ear. The lesion showed contrast enhancement after contrast media administration in T1 sequence. The final diagnosis was otitis interna. The ferret was hospitalized and received intravenous fluids, oral enrofloxacin, and prednisolone. Clinical signs rapidly improved with treatment and the ferret was discharged after 5 days in the hospital. Treatment was continued for a further 15 days. Six months later, the ferret was healthy and not displaying any neurologic signs. Otitis interna should be included in the differential diagnosis for peripheral vestibular syndrome in ferrets. This case report highlights the importance of advanced imaging techniques to reach a definitive diagnosis.
摘要译文
雪貂很少报道前庭体征。该报告证明了在雪貂中成功诊断和治疗无内耳炎的中耳炎。一只4岁的去甲肾上腺素植入的雌性雪貂，发病初期为2天，在右侧盘旋和掉落，食欲减退。神经系统检查发现右侧头倾斜与双侧水平眼球震颤有关，其左侧为快速相。这些发现强烈暗示了右侧前庭综合征。完整的血细胞计数，血清生化指标和CT扫描均无异常。大脑1.5T对比增强磁共振成像扫描显示右内耳有一个低点的T2信号异常，而中耳没有受累。在按T1顺序施用造影剂后，病变显示造影剂增强。最终诊断为内耳炎。雪貂入院并接受静脉输液，口服恩诺沙星和泼尼松龙。治疗后临床症状迅速改善，雪貂在医院治疗5天后出院。继续治疗另外15天。六个月后，雪貂健康，没有出现任何神经系统症状。在雪貂外围前庭综合征的鉴别诊断中应包括内耳炎。该病例报告强调了先进的成像技术对做出明确诊断的重要性。
IsabelleDesprezDVM[a];Thomas M.DonnellyBVSc; Dip. ECZM (SM); Dip. ACLAM; Dip. ABVP (ECM)[a];VincentMayousseDVM[b];Jean-LaurentThibaudDVM; Dip. ECVN[c];Dennilyn L.ParkerDVM; Dip. ABVP (Avian)[d];CharlyPignonDVM; Dip. ECZM (SM)[a]. A case of otitis interna in a ferret (Mustela putorius furo)[J]. Journal of Exotic Pet Medicine, 2019,31: 104-107