期刊文献

Alpha mangostin Inhibits Hepatic Stellate Cells Activation Through TGF-β/Smad and Akt Signaling Pathways: An in vitro Study in LX2 收藏

阿尔法芒果抑制通过TGF-β/ Smad和Akt信号通路的肝星状细胞激活：在LX2的体外研究。
原文求助 发布源
作者
Rahmaniah Rahmaniah;Yuyuntia Yuyuntia;Vivian Soetikno;Wawaimuli Arozal;Radiana Dhewayani Antarianto;Melva Louisa
关键词
Alpha mangostin;hepatic stellate cells;TGF-β;Smad;Akt
关键词译文
芒果；肝星状细胞；TGF-β； Smad； Akt
发布日期
2017/10/09
页码
153-158
DOI
10.1055/s-0043-119074
来源信息
Drug Research ISSN：2194-9379, 2018年, 68卷, 03期, 153-158页
摘要
Background Alpha mangostin has been reported to have activity for the treatment of liver fibrosis in the rats. However, the mechanisms of action are poorly understood. This study was aimed to investigate the effect of alpha mangostin on hepatic stellate cells (HSC) activation and proliferation through TGF-β/Smad and Akt signaling pathways.
摘要译文
背景技术据报道，α-芒果素具有治疗大鼠肝纤维化的活性。但是，作用机理了解得很少。本研究旨在探讨α-芒果素通过TGF-β/ Smad和Akt信号通路对肝星状细胞（HSC）活化和增殖的影响。
Rahmaniah Rahmaniah;Yuyuntia Yuyuntia;Vivian Soetikno;Wawaimuli Arozal;Radiana Dhewayani Antarianto;Melva Louisa. Alpha mangostin Inhibits Hepatic Stellate Cells Activation Through TGF-β/Smad and Akt Signaling Pathways: An in vitro Study in LX2[J]. Drug Research, 2018,68(03): 153-158