摘要
Traditional Chinese medicine-based herbal medicines have gained increasing acceptance worldwide in recent years and are being pursued by pharmaceutical companies as rich resources for drug discovery. For many years, traditional Chinese medicines (TCM) have been applied for the treatment of cancers in China and beyond. Herbal medicines are generally low in cost, plentiful, and show very little toxicity or side effects in clinical practice. However, despite the vast interest and ever-increasing demand, the absence of strong evidence-based research and the lack of standardization of the herbal products are the main obstacles toward the globalization of TCM. In recent years, TCM research has greatly accelerated with the advancement of analytical technologies and methodologies. This review of TCM specifically used in the treatment of cancer is divided into two parts. Part one provides an overview of the philosophy, approaches and progress in TCM-based cancer therapy. Part two summarizes the current understanding of how TCM-derived compounds function as anticancer drugs.
摘要译文
近年来，以中草药为基础的中草药在世界范围内得到越来越多的接受，并且制药公司正在将其作为丰富的发现药物的资源而追求。多年来，在中国及其他地区，中药一直被用于治疗癌症。草药通常成本低廉，丰富，并且在临床实践中几乎没有毒性或副作用。然而，尽管人们的兴趣浓厚且需求不断增长，但缺乏有力的证据基础的研究以及草药产品的标准化是中医药全球化的主要障碍。近年来，随着分析技术和方法学的发展，中药研究大大加速。这篇专门用于癌症治疗的中医综述分为两个部分。第一部分概述了基于中医的癌症治疗的理念，方法和进展。第二部分总结了当前对中药来源的化合物如何作为抗癌药的理解。
W. L. Wendy Hsiao;Liang Liu. The Role of Traditional Chinese Herbal Medicines in Cancer Therapy – from TCM Theory to Mechanistic Insights[J]. Planta Medica, 2010,76(11): 1118-1131