摘要
The objectives of this study were to assess the effects of Saccharomyces cerevisiae fermentation products (SCFP; NaturSafe, SCFPns; and Original XPC, XPC; Diamond V) on growth performance, carcass traits, immune response, and antimicrobial resistance in beef steers fed high-grain diets. Ninety Angus steers (initial body weight [BW], 533 ± 9.8 kg) were assigned to a randomized complete design with 6 treatments (n = 15/treatment): 1) control, 2) low (12 g SCFPns·steer−1·d−1), 3) medium (15 g SCFPns·steer−1·d−1), 4) high SCFP (18 g SCFPns·steer−1·d−1), 5) encapsulated XPC (eXPC; 7 g XPC·steer−1·d−1 encapsulated with 9 g capsule material), and 6) antibiotics (ANT; 330 mg monensin + 110 mg tylosin·steer−1·d−1). Steers were fed ad libitum a diet containing 10% barley silage and 90% barley grain concentrate mix (dry matter basis) for 105 d. Increasing SCFPns tended (P < 0.09) to linearly increase feed efficiency. Average daily gain (ADG) tended (P < 0.10) to be greater in steers supplemented with eXPC than control. The SCFPns also tended (P < 0.10) to linearly increase marbling score. Proportion of severely abscessed livers tended (P < 0.10) to be lower in steers supplemented with medium and high SCFPns, eXPC, or ANT. A treatment × days on feed interaction were noticed (P < 0.01) for blood glucose, blood urea nitrogen (BUN), and acute phase proteins. The concentration of blood glucose responded quadratically (P < 0.05) on days 28 and 56, whereas BUN linearly (P < 0.01) increased on day 105 with increasing SCFPns dose. The SCFPns linearly increased haptoglobin (P < 0.03) and serum amyloid A (SAA;P < 0.05) concentrations on day 105, and lipopolysaccharide binding protein (LBP;P < 0.01) on days 56 and 105. The percentage of erythromycin-resistant and erythromycin + tetracycline-resistant enterococci was greater (P < 0.05) with ANT than control, SCFPns, and eXPC, whereas no difference was observed among control, SCFPns, and eXPC. No treatment effect was detected on the percentage of tetracycline-resistant enterococci. These results indicate that feeding SCFPns and eXPC was beneficial in improving ADG, feed efficiency and decreasing liver abscesses in a manner comparable to ANT. Unlike antibiotics, SCFPns or eXPC did not increase antimicrobial resistance. Both SCFPns and eXPC are potential alternatives to in-feed antibiotics.
摘要译文
本研究的目的是评估酿酒酵母发酵产物（SCFP）的作用。 NaturSafe，SCFPns；和原始XPC，XPC；钻石V）对高谷物饮食的牛肉beef牛的生长性能，car体性状，免疫反应和抗微生物性有影响。将90头安格斯ste牛（初始体重[BW]，533±9.8千克）分配到6种处理方法（n = 15 /处理）的随机完整设计中：1）对照，2）低（12 g SCFPns·steer -1 ·d -1 ），3）中型（15 g SCFPns·steer -1 ·d -1 ）， 4）高SCFP（18 g SCFPns·steer −1 ·d -1 ），5）封装的XPC（eXPC； 7 g XPC·steer -1 ·d -1 用9 g胶囊材料封装）和6）抗生素（ANT； 330毫克莫能菌素+ 110毫克泰乐菌素·转向 -1 ·d -1 ）。雄性饲喂含10％大麦青贮饲料和90％大麦籽粒浓缩饲料（以干物质为基础）的饲料105 d。 SCFPns的增加趋向于（P <0.09）线性增加饲料效率。补充eXPC的ste牛的平均日增重（ADG）趋于（P <0.10）比对照大。 SCFPns也倾向于（P <0.10）线性增加大理石花纹分数。补充中度和高度SCFPns，eXPC或ANT的ers牛中，严重脓肿的肝脏比例往往较低（P <0.10）。血糖，血尿素氮（BUN）和急性期蛋白在饲料相互作用上的处理量×处理天数（P <0.01）。随着SCFPns剂量的增加，血糖浓度在第28天和第56天呈二次响应（P <0.05），而在第105天BUN呈线性（P <0.01）线性增加（P <0.01）。在第105天时SCFPns线性增加触珠蛋白（P <0.03）和血清淀粉样蛋白A（SAA; P <0.05）的浓度，在第56天和105天线性增加脂多糖结合蛋白（LBP; P <0.01）。红霉素+四环素对肠球菌的耐药性比对照组，SCFPns和eXPC大（P <0.05），而对照组，SCFPns和eXPC之间没有差异。未检测到对四环素耐药肠球菌百分数的治疗效果。这些结果表明，饲喂SCFPns和eXPC以与ANT相当的方式有益于改善ADG，饲喂效率和减少肝脓肿。与抗生素不同，SCFPns或eXPC不会增加抗药性。 SCFPns和eXPC都是饲料中抗生素的潜在替代品。
Yizhao Shen; Taylor Davedow; Tao Ran; Atef M Saleem; Ilkyu Yoon. "Ruminally protected and unprotected Saccharomyces cerevisiae fermentation products as alternatives to antibiotics in finishing beef steers"[J]. Journal of Animal Science, 2019,97(10): 4323-4333