期刊文献

Obesity and Cancer: The Role of Dysfunctional Adipose Tissue 收藏

肥胖和癌症：功能失调的作用脂肪组织
原文求助 发布源
作者
Rob C.M. van Kruijsdijk ;Elsken van der Wall ;Frank L.J. Visseren
发布日期
October 2009
页码
2569-2578
DOI
10.1158/1055-9965.EPI-09-0372
来源信息
Cancer Epidemiology, Biomarkers & Prevention ISSN：1055-9965, 2009年, 18卷, 10期, 2569-2578页
摘要
Overweight and obesity are health problems of epidemic proportions, increasing the risk not only of cardiovascular disease and type 2 diabetes mellitus but also of various types of cancer. Obesity is strongly associated with changes in the physiological function of adipose tissue, leading to insulin resistance, chronic inflammation, and altered secretion of adipokines. Several of these factors, such as insulin resistance, increased levels of leptin, plasminogen activator inhibitor-1, and endogen
摘要译文
超重和肥胖是流行性比例的健康问题，不仅增加了心血管疾病的风险，而且患2型糖尿病，也是各种类型的癌症。肥胖与脂肪组织的生理功能的变化强烈有关，导致胰岛素抵抗，慢性炎症和脂肪因子的分泌改变。这些因素中的一些，例如胰岛素抵抗，瘦素水平增加，纤溶酶原激活剂抑制剂-1和内源性
Rob C.M. van Kruijsdijk ;Elsken van der Wall ;Frank L.J. Visseren. Obesity and Cancer: The Role of Dysfunctional Adipose Tissue[J]. Cancer Epidemiology, Biomarkers & Prevention, 2009,18(10): 2569-2578