摘要
Simple Summary Paratuberculosis is a chronic disease of ruminants and many non-ruminant animals caused by the bacterium Mycobacterium avium subsp. paratuberculosis. Affected animals show diarrhoea, loss of weight, and decreased production performance with consequent economic losses. This bacterium has been detected in some humans suffering from a chronic intestinal disease known as Crohn’s disease (CD) and, therefore, some scientists believe that CD is the human form of paratuberculosis. The disease in small ruminants has been reported in all continents, with goats being more susceptible than sheep. The clinical signs of the disease in goats are not so obvious as often do not show signs of diarrhoea, and the animal may die before being finally diagnosed. In Africa and many developing countries, paratuberculosis is described as a “neglected disease” particularly in small ruminants, which play a vital role in the livelihood of poor communities. This overview attempts to highlight the current research and gaps on this disease in small ruminants to draw more attention for further studies on diagnosis, prevention and control.
摘要译文
简单的摘要旁结核病是反刍动物的慢性疾病和许多由细菌分枝杆菌亚种引起的非鲁um虫动物。副结核病。受影响的动物表现出腹泻，体重减轻以及随之而来的经济损失，生产效果降低。在一些患有慢性肠道疾病的人（CD）的人类中已经发现了这种细菌，因此，一些科学家认为CD是旁核的人类形式。据报道，各大洲的小反刍动物中的这种疾病，山羊比绵羊更容易受到影响。山羊疾病的临床体征并不是那么明显，因为通常不会显示腹泻的迹象，并且该动物可能在最终被诊断出去之前死亡。在非洲和许多发展中国家，旁核核病被描述为一种“被忽视的疾病”，尤其是在小型反刍动物中，在贫困社区的生计中起着至关重要的作用。该概述试图强调当前的研究和小型反刍动物的差距，以更多地注意诊断，预防和控制的进一步研究。
Sanaa M. Idris;1;2 Kamal H. Eltom;1;* Julius B. Okuni;3 Lonzy Ojok;3;4 Wisal A. Elmagzoub;1;5 Ahmed Abd El Wahed;6;* ElSagad Eltayeb;7;Ahmed A. Gameel2Sanaa M. Idris1Department of Animal Health;Safety of Animal Products; Institute for Studies;Promotion of Animal Exports; University of Khartoum; Shambat 13314; Khartoum North; Sudan; moc.liamg@51sirdiaanas (S.M.I.); moc.liamg@buozgamlelasiw (W.A.E.)2Department of Pathology; Faculty of Veterinary Medicine; University of Khartoum; Shambat 13314; Khartoum North; Sudan; moc.liamtoh@leemagraaFind articles by Sanaa M. Idris. Paratuberculosis: The Hidden Killer of Small Ruminants[J]. Animals : an Open Access Journal from MDPI, 2022,12(1)