摘要
The course of disease was studied in 8 cattle infected with Trypanosoma congolense. Although the onset of patency was dependent on the numbers of infecting organisms, the duration of the infection was not. High fevers were present on the day of or the day after initial patency. Succeeding peaks of parasitemia, and a progressive weight loss of over 30% occurred. A decrease in packed cell volume (PCV) beginning the first week after infection was observed. Early in the course of the developing anemia, many polychromatophilic erythrocytes and occasional normoblasts were found in the blood. A leucopenia persisted for the duration of the disease. Total serum protein concentrations fell sharply during the first 5 weeks of infection, then gradually increased to low normal levels. Serum albumin levels followed a similar pattern for the first 5 weeks, and remained at a relatively low level. Although gamma globulin levels also declined during the first 5 weeks, their levels gradually surpassed those of preinfection samples. No marked changes in serum glucose were noted. A mild elevation of serum urea nitrogen values occurred early during infection, but subsided. The animals dying early after infection developed elevated total bilirubin levels.
摘要译文
在感染了锥虫（Trypanosoma congolense）的8头牛中研究了病程。虽然通畅的开始取决于感染生物的数量，但感染的持续时间却没有。在初次通畅的当天或第二天出现高烧。寄生虫血症的峰值成功，并且累积的体重减轻超过30％。观察到感染后第一周开始的包装细胞体积（PCV）降低。在发展中的贫血症的早期，血液中发现了许多多色红细胞和偶然的正常成血细胞。白细胞减少症在疾病持续期间持续存在。在感染的前5周，总血清蛋白浓度急剧下降，然后逐渐升高至低正常水平。前5周血清白蛋白水平遵循相似的模式，并保持在相对较低的水平。虽然前5周内丙种球蛋白水平也下降，但它们的水平逐渐超过了预感染样本。没有注意到血清葡萄糖的显着变化。感染早期血清尿素氮值轻度升高，但消退。感染后早期死亡的动物的总胆红素水平升高。
B.Wellde[2];R.Lötzsch[1];G.Deindl[1];E.Sadun[2];J.Williams[2];G.Warui[1];. Trypanosoma congolense[J]. Experimental Parasitology, 1974,36(1): 6-19