摘要
Mycotoxins are a major threat to animal and human health, as well as to the global feed supply chain. Among them, aflatoxins, fumonisins, zearalenone, T-2 toxins, deoxynivalenol, and Alternaria toxins are the most common mycotoxins found in animal feed, with genotoxic, cytotoxic, carcinogenic, and mutagenic effects that concern the animal industry. The chronic negative effects of mycotoxins on animal health and production and the negative economic impact on the livestock industry make it crucial to develop and implement solutions to mitigate mycotoxins. In this review, we summarize the current knowledge of the mycotoxicosis effect in livestock animals as a result of their contaminated diet. In addition, we discuss the potential of five promising phytogenics (curcumin, silymarin, grape pomace, olive pomace, and orange peel extracts) with demonstrated positive effects on animal performance and health, to present them as potential anti-mycotoxin solutions. We describe the composition and the main promising characteristics of these bioactive compounds that can exert beneficial effects on animal health and performance, and how these phytogenic feed additives can help to alleviate mycotoxins’ deleterious effects.
摘要译文
霉菌毒素是对动物和人类健康以及全球饲料供应链的主要威胁。其中，黄曲霉毒素，富莫尼蛋白，Zearalenone，T-2毒素，脱氧烯醇和替代毒素是动物饲料中发现的最常见的霉菌毒素，具有与动物行业有关的遗传毒性，细胞毒性，致癌和诱变作用。霉菌毒素对动物健康和生产以及对牲畜行业的负面影响的慢性负面影响使开发和实施解决霉菌毒素至关重要。在这篇综述中，我们总结了由于饮食受污染的饮食，目前对牲畜动物的霉菌毒性作用的知识。此外，我们讨论了五种有前途的植物基因（姜黄素，水飞蓟素，葡萄黄绿色，橄榄果片和橙皮提取物）的潜力，对动物性能和健康表现出积极的影响，以表现为潜在的抗肌毒素解决方案。我们描述了这些生物活性化合物的组成和主要有希望的特征，这些化合物可以对动物的健康和性能产生有益的影响，以及这些植物源性饲料添加剂如何有助于减轻霉菌毒素的有害作用。
Sergio Quesada-Vázquez; Raquel Codina Moreno; Antonella Della Badia; Oscar Castro; Insaf Riahi. Promising Phytogenic Feed Additives Used as Anti-Mycotoxin Solutions in Animal Nutrition[J]. Toxins, 2024,16(10): 434