摘要
Malignant catarrhal fever (MCF) is an infectious, pansystemic and highly fatal disease with wide geographic distribution. The species that are clinically prone to it include cattle, deer and bison. In Brazil, the disease in ruminants and deer is associated with the contact with sheep, especially during labor, when the fetal remains that are eliminated contain the ovine herpesvirus 2 (OvHV-2). The outbreak took place in a conservationist property in the city of Casimiro de Abreu/RJ, which hosted 23 Sambar deer, and, of these, 19 died, showing neurological signs. The deer lived in a location together with 15 male and female meat sheep. A female specimen of the Sambar deer (Rusa unicolor), aged approximately three years, which had presented with neurological clinical signs was referred to necropsy in the Setor de Anatomia Patológica at Universidade Federal Rural do Rio de Janeiro (SAP/UFRRJ). During necropsy, cerebrospinal fluid was sampled for analysis; fragments of several organs were fixated in 10% buffered formalin and processed for histopathological analysis. Fragments of occipital lobe, cerebellum and bulb were collected to perform the polymerase chain reaction (PCR). The diagnosis of this outbreak was based on epidemiological, clinical and pathological findings, and on the amplification of the OvHV-2 DNA through PCR. The histological changes were the base to confirm the MCF case and were characterized by degeneration of vascular endothelial cells, fibrinoid vasculitis, hyperplasia and necrosis of lymphoid organs. However, PCR was an important tool to confirm the diagnosis. MCF as an important disease with nervous symptomatology in deer.
摘要译文
恶性卡他性热病（MCF）是一种具有广泛地理分布的传染性，非系统性和高致命性疾病。临床上容易发生的物种包括牛，鹿和野牛。在巴西，反刍动物和鹿的疾病与羊的接触有关，特别是在分娩期间，当被消除的胎儿遗体含有羊疱疹病毒2（OvHV-2）时。疫情发生在Casimiro de Abreu / RJ市的一个保护主义财产中，该地区饲养了23只水鹿，其中19只死亡，显示出神经系统症状。鹿与15只雄性和雌性肉羊一起生活在一个地方。在里约热内卢联邦农村大学（SAP / UFRRJ）的Setor deAnatomiaPatológica中，一只雌性标本的Sambar鹿（Rusa unicolor），年龄大约为3年，已经出现了神经系统临床症状。尸检时，取脑脊液进行分析;将几个器官的片段固定在10％缓冲的福尔马林中并处理用于组织病理学分析。收集枕叶，小脑和球茎的碎片以进行聚合酶链反应（PCR）。这次暴发的诊断基于流行病学，临床和病理学发现，以及通过PCR扩增OvHV-2 DNA。组织学变化是确认MCF病例的基础，其特征在于血管内皮细胞的变性，纤维蛋白样血管炎，淋巴器官的增生和坏死。然而，PCR是确认诊断的重要工具。 MCF是一种重要的疾病，在鹿中具有神经症状。
OLIVEIRA, Mariana C. et al.. An outbreak of malignant catarrhal fever in Sambar deer (Rusa unicolor).[J]. Pesquisa Veterinária Brasileira, 2018,38(8): 1675-1680