期刊文献

Comparison of fallopian tube sperm perfusion with intrauterine insemination in the treatment of infertility 收藏

输卵管精子灌注与宫腔内人工授精治疗不孕症的比较

原文求助发布源

作者

SinikkaNuojua-HuttunenM.D.[∗][‡];LeenaTuomivaaraPh.D.[‡];KaisaJuntunenM.D.[‡];Ph.D.CandidoTomás[∗];HannuMartikainenPh.D.[∗];

作者单位

[∗]Department of Obstetrics and Gynecology, Oulu University Hospital, Oulu, Finland[‡]The Oulu Infertility Clinic, The Family Federation of Finland, Oulu, Finland[†]Reprint requests: Sinikka Nuojua-Huttunen, M.D., Department of Obstetrics and Gynecology, University of Oulu, Kajaanintie 50, FIN-90220 Oulu, Finland (FAX: 358-8-5372563).

关键词

Fallopian tube sperm perfusion; intrauterine insemination; infertility; ovulation induction; assisted reproductive technology;

关键词译文

输卵管精子灌注;宫腔内人工授精;不孕;排卵诱导;辅助生殖技术;

发布日期

1 May 1997

页码

939-942

DOI

10.1016/S0015-0282(97)81411-2

来源信息

Fertility and Sterility ISSN：0015-0282, 1997年, 67卷, 5期, 939-942页

摘要

Objective: To compare the efficacy of fallopian tube sperm perfusion utilizing a Foley catheter technique with standard IUI. Design: Randomized controlled study. Setting: The infertility units of the University Central Hospital and the Family Federation of Finland, Oulu, Finland. Patient(s): One hundred infertile women with unexplained factor, minimal to mild endometriosis, mild male factor, or ovarian dysfunction, undergoing 50 IUI and 50 fallopian tube sperm perfusion cycles stimulated by clomiphene citrate and hMG. Intervention(s): Thirty-six hours after hCG administration, patients were randomized to either the IUI group (group 1, 50 patients and cycles) or the fallopian tube sperm perfusion group (group 2, 50 patients and cycles). Intrauterine insemination was performed using a standard method and fallopian tube sperm perfusion with a pediatric Foley catheter, which prevents the reflux of sperm suspension. Main Outcome Measure(s): Number of clinical pregnancies. Result(s): The fallopian tube sperm perfusion method using a Foley catheter technique was easy to perform and convenient for the patients. The overall pregnancy rate per cycle was 8% for fallopian tube sperm perfusion and 20% for IUI, a difference that was not significant. Conclusion(s): The fallopian tube sperm perfusion method using a Foley catheter offers no advantage in comparison with the conventional IUI technique.

摘要译文

目的：比较Foley导管技术与标准IUI输卵管精子灌注的疗效。设计：随机对照研究。地点：芬兰奥卢大学中心医院和芬兰家庭联合会的不孕不育单位。患者：100名不明原因，少数至轻度子宫内膜异位症，轻度男性因素或卵巢功能障碍的不孕妇女，接受由克罗米芬和hMG刺激的50例IUI和50例输卵管精子灌注周期。干预：hCG给药后36小时，患者随机分为IUI组（第1组，50名患者和周期）或输卵管精子灌注组（第2组，50名患者和周期）。使用标准方法和输卵管精子灌注用小儿Foley导管进行子宫内人工授精，该导管可防止精子悬浮液的回流。主要指标：临床妊娠次数。结果：采用Foley导管技术的输卵管精子灌注方法易于操作，方便患者使用。输卵管精子灌注的每个周期的总体妊娠率为8％，IUI为20％，差异不显着。结论：与传统的IUI技术相比，使用Foley导管的输卵管精子灌注方法没有任何优势。

SinikkaNuojua-HuttunenM.D.[∗][‡];LeenaTuomivaaraPh.D.[‡];KaisaJuntunenM.D.[‡];Ph.D.CandidoTomás[∗];HannuMartikainenPh.D.[∗];. Comparison of fallopian tube sperm perfusion with intrauterine insemination in the treatment of infertility[J]. Fertility and Sterility, 1997,67(5): 939-942