摘要
The effects of prebiotics on digestibility, short-chain fatty acid (SCFA) concentrations and bacterial populations in the faeces and immunity in dogs were evaluated by meta-analyses. Overall, data from 15 published studies containing 65 different treatment means of 418 observations from different breeds of dogs were included in the data set. Feeding of prebiotics to dogs did not affect the nutrient intake (P > 0.10), nor did prebiotics change (P > 0.10) the digestibility of dry matter (DM) and fat. However, crude protein (CP) digestibility tended to decrease quadratically (P = 0.06) with increasing dosages of prebiotics, although the degree of prediction was low (R2 = 0.33). The concentration of total SCFA (P = 0.08; R2 = 0.90) tended to increase linearly, whereas concentration of acetate (R2 = 0.25), propionate (R2 = 0.88) and butyrate (R2 = 0.85) increased quadratically with increasing dosage of prebiotics in the faeces of dogs. The numbers of beneficial bifidobacteria (P R2 = 0.62) increased quadratically, but lactobacilli (P R2 = 0.66) increased linearly with increasing supplementation of prebiotics. The changes in healthy bacterial numbers were affected by the interaction of initial bacterial numbers and dose of prebiotics; bacterial numbers increased relatively more when initial bacterial numbers were low. Dietary composition did not influence the response of prebiotics on lactobacilli and bifidobacterial numbers in this study. The numbers of pathogenic Clostridium perfringens and Escherichia coli were not affected by prebiotics. Prebiotics did not affect the serum immunoglobulin (Ig) concentrations such as IgG, IgA and IgM in dogs. Although prebiotics may tend to have an adverse effect on CP digestibility, prebiotics at doses up to 1.40% food intake (DM basis) might increase the beneficial bacterial populations and SCFA concentrations in the faeces of dogs. Thus, the feeding of prebiotics has a great prospective to improve the intestinal health of dogs.
摘要译文
通过荟萃分析评估益生元对粪便中消化率，短链脂肪酸（SCFA）浓度和细菌群体以及狗免疫力的影响。总体而言，数据集中包括来自15个已发表研究的数据，这些研究包含来自不同品种的狗的418个观察结果的65种不同治疗方法。向狗喂食益生元不会影响营养素的摄入（P> 0.10），益生元也不会改变（P> 0.10）干物质（DM）和脂肪的消化率。然而，随着益生元剂量的增加，粗蛋白（CP）的消化率趋于平方降低（P = 0.06），尽管预测程度较低（R2 = 0.33）。总SCFA浓度（P = 0.08; R2 = 0.90）倾向于线性增加，而乙酸盐（R2 = 0.25），丙酸盐（R2 = 0.88）和丁酸盐（R2 = 0.85）的浓度随着狗粪便中益生元剂量的增加而呈二次方增加。有益双歧杆菌的数量（P R2 = 0.62）呈二次方增加，但乳酸杆菌（P R2 = 0.66）随着益生元补充的增加呈线性增加。健康细菌数量的变化受初始细菌数量与益生元剂量相互作用的影响;当初始细菌数量较少时，细菌数量相对增加。在本研究中，膳食组合物不影响益生元对乳酸杆菌和双歧杆菌数量的反应。致病性产气荚膜梭菌和大肠杆菌的数量不受益生元的影响。益生元不影响狗的血清免疫球蛋白（Ig）浓度，例如IgG，IgA和IgM。虽然益生元可能会对CP的消化率产生不利影响，但在食物摄入量（DM基础）高达1.40％的剂量下，益生元可能会增加狗粪便中的有益细菌数量和SCFA浓度。因此，益生元的喂养对于改善狗的肠道健康具有很大的前景。
A. K. Patra (a1). Responses of feeding prebiotics on nutrient digestibility, faecal microbiota composition and short-chain fatty acid concentrations in dogs: a meta-analysis[J]. animal, 2011,5(11): 1743-1750