摘要
Most respiratory oxidases of eukaryotic and prokaryotic organisms are members of a superfamily of enzymes that couple the redox energy available from the reduction of molecular oxygen to the mechanism of pumping protons across the membrane. The recent applications of site-directed mutagenesis and of a variety of spectroscopic techniques have allowed major advances in our understanding of the structure and function of these proteins.
摘要译文
真核生物和原核生物的大多数呼吸氧化酶是酶的超家族的成员，其将从分子氧的还原中获得的氧化还原能量耦合到跨质膜泵送质子的机制。最近的定点诱变和各种光谱技术的应用使我们对这些蛋白质的结构和功能的理解取得了重大进展。
Melissa W. Calhoun Jeffrey W. Thomas Robert B. Gennis. The cytochrome oxidase superfamily of redox-driven proton pumps[J]. Trends in Biochemical Sciences, 1994,19(8): 325-330