期刊文献

The Candidate Sour Taste Receptor, PKD2L1, Is Expressed by Type III Taste Cells in the Mouse 收藏

候选酸味受体PKD2L1，由小鼠中的III型味道细胞表达

原文求助发布源

作者

Shinji Kataoka [1]; Ruibiao Yang [1]; Yoshiro Ishimaru [2]; Hiroaki Matsunami [2]; Jean Sévigny [3]; John C. Kinnamon [1]; Thomas E. Finger [1]

作者单位

[1]1Rocky Mountain Taste & Smell Center;[2]4Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA;[3]6Centre de Recherche en Rhumatologie et Immunologie, Centre Hospitalier Universitaire de Québec, Université Laval, Québec, QC, Canada

关键词

gustation;mouse;polycystic kidney disease–like ion channel (PKD2L1);sour taste;taste bud cells

关键词译文

烧烤;小鼠;多囊肾病如离子通道（PKD2L1）;酸味;味蕾细胞

发布日期

21 December 2007

页码

243-254

DOI

10.1093/chemse/bjm083

来源信息

Cerebral Cortex ISSN：1047-3211, 2008年, 33卷, 3期, 243-254页

摘要

The transient receptor potential channel, PKD2L1, is reported to be a candidate receptor for sour taste based on molecular biological and functional studies. Here, we investigated the expression pattern of PKD2L1-immunoreactivity (IR) in taste buds of the mouse. PKD2L1-IR is present in a few elongate cells in each taste bud as reported previously. The PKD2L1-expressing cells are different from those expressing PLCβ2, a marker of Type II cells. Likewise PKD2L1-immunoreactive taste cells do n

摘要译文

据报道，瞬时受体电位通道PKD2L1是基于分子生物学和功能性研究的酸性味的候选受体。在这里，我们研究了小鼠的味蕾的PKD2L1-免疫反应性（IR）的表达模式。如前所述，PKD2L1-IR在每种味蕾中的几个细胞中存在。表达PKD2L1的细胞与表达PLCβ2的细胞不同，II型细胞的标记物。同样，PKD2L1-免疫反应细胞DO

Shinji Kataoka [1]; Ruibiao Yang [1]; Yoshiro Ishimaru [2]; Hiroaki Matsunami [2]; Jean Sévigny [3]; John C. Kinnamon [1]; Thomas E. Finger [1]. The Candidate Sour Taste Receptor, PKD2L1, Is Expressed by Type III Taste Cells in the Mouse[J]. Cerebral Cortex, 2008,33(3): 243-254