摘要
One hundred twenty-eight couples undergoing intrauterine inseminations were retrospectively reviewed. Life table methodology was used to analyze cumulative pregnancy rates and monthly fecundability. Respective 6- and 12-month cumulative pregnancy rates for each diagnostic group receiving intrauterine insemination were: cervical factor, 28.6% and 42.8%; male factor, 16.7% and 16.7%; female immune factor, 66.7% and 100.0%; male immune factor, 37.5% and 68.8%; and empiric treatment, 60.0% and 60.0%. There was no difference in pregnanacy rates between sperm processed with a swim-up in Ham's F-10 or a two-gradient Percoll system. Abnormal sperm penetration assay results in patients with male factor did significantly (p = 0.05) lower the pregnancy rate. It is concluded that if no pregnancy has occurred after six cycles of inseminations, further workup or other treatment may be initiated, but additional pregnancies can be achieved from the seventh through the twelfth cycles of intrauterine insemination
摘要译文
对188名接受宫内受精的夫妇进行了回顾性分析。生命表方法用于分析累积妊娠率和每月生育能力。每个接受宫腔内人工授精的诊断组的6个月和12个月累积妊娠率分别为：宫颈因子，28.6％和42.8％;男性因素，16.7％和16.7％;女性免疫因子，66.7％和100.0％;男性免疫因子，37.5％和68.8％;和经验治疗，60.0％和60.0％。在Ham''''s F-10或双梯度Percoll系统中用游泳处理的精子之间的妊娠率没有差异。异常精子穿透试验结果显示，男性因素患者的妊娠率明显降低（p \x3d 0.05）。结论是，如果在六个授精周期后没有发生怀孕，可以开始进一步的检查或其他治疗，但是从宫内人工授精的第7到第12个周期可以实现额外的怀孕
Roger A.LalichDO;Edward L.MarutMD;Gail S.PrinsPhD;AntonioScommegnaMD;. Life table analysis of intrauterine insemination pregnancy rates[J]. American Journal of Obstetrics and Gynecology, 1988,158(4): 980-984