摘要
Recent molecular-based investigations have confirmed the species diversity and metabolic complexity of the human gut microbiota. It is also increasingly clear that the human gut microbiota plays a crucial role in host health, both as a source of infection and environmental insult and, conversely, in protection against disease and maintenance of gut function. Although little is known about the health impact of the dominant groups of gut bacteria it is generally accepted that bifidobacteria and lactobacilli are important components of what might be termed the beneficial gut microbiota. The microbiota management tools of probiotics, prebiotics and synbiotics have been developed and, indeed, commercialized over the past few decades with the expressed purpose of increasing numbers of bifidobacteria and/or lactobacilli within the gastrointestinal tract.
摘要译文
最近基于分子的研究证实了人类肠道微生物群的物种多样性和代谢复杂性。同样越来越清楚的是，人类肠道微生物群在宿主健康中起着至关重要的作用，既是感染源又是环境污染，相反，它们在防止疾病和维持肠道功能方面。尽管对肠道细菌主要群体对健康的影响知之甚少，但人们普遍认为双歧杆菌和乳酸杆菌是可能被称为有益肠道微生物群的重要组成部分。益生菌，益生元和合生元的微生物群管理工具已经开发出来，并且实际上在过去几十年中商业化，其目的是在胃肠道内增加双歧杆菌和/或乳酸杆菌的数量。
Kieran M Tuohy k.m.tuohy@reading.ac.uk Hollie M Probert Chris W Smejkal Glann R Gibson. Using probiotics and prebiotics to improve gut health[J]. Drug discovery today, 2003,8(15): 692-700