摘要
Leptospirosis is a global disease of animals, with potential major economic impact on livestock industry and important zoonotic capacities. The disease represents a major challenge in the developing countries as humans and animals frequently live in close association. The serovar Hardjo of Leptospira whose primary host is cattle has been studied extensively, but few data exist on other current circulating or emerging serotypes. To better understand the disease in cattle and how to prevent and/or control it, it is necessary to identify the genotype and the serotype of circulating Leptospira. This study presents results of several investigations performed on a historical Belgian collection of congenital jaundice in bovine aborted foetuses coming from the leptospirosis emerging episode of 2014 (Delooz et al., Transboundary and Emerging Diseases, 62, 2015, 124). The results revealed that L. Grippotyphosa and L. Australis were the most prevalent serogroups with, respectively, 17/42 and 13/42 positive microscopic agglutination test (MAT) during this emerging event associated with the same clinical pattern. The study also confirms that congenital jaundice is associated with L. kirscheneri and L. interrogans and provides the genotyping of DNA obtained from these two species.
摘要译文
钩端螺旋体病是动物的全球性疾病，对畜牧业和重要的人畜共患病能力具有潜在的重大经济影响。由于人类和动物经常生活在密切的联系中，因此这种疾病在发展中国家是一个重大挑战。主要寄主为牛的钩端螺旋体的血清型Hardjo已被广泛研究，但其他目前流行或新出现的血清型中存在的数据很少。为了更好地了解牛的疾病以及如何预防和/或控制它，有必要确定循环钩端螺旋体的基因型和血清型。对2014年出现钩端螺旋体病新出现事件的牛流产胎儿中历史比利时收集的先天性黄疸进行了几项调查结果（Delooz et al。，Transboundary and Emerging Diseases，62,2015,124）。结果显示L. Grippotyphosa和L. Australis分别是最普遍的血清群，17/42和13/42阳性显微凝集试验（MAT）在与相同临床模式相关的这一新兴事件中。该研究还证实，先天性黄疸与L. kirscheneri和问号钩端螺旋体有关，并提供了从这两个物种获得的DNA的基因分型。
L. Delooz[1,2]; G. Czaplicki[1]; F. Gregoire[1]; F. Dal Pozzo[2]; F. Pez[3]; A. Kodjo[4] and C. Saegerman[2,*];. Serogroups and genotypes of Leptospira spp. strains from bovine aborted foetuses[J]. Transboundary and Emerging Diseases, 2018,65(1): 158-165