期刊文献

Associations of the Polymorphisms in DHRS4, SERPING1, and APOR Genes with Postmortem pH in Berkshire Pigs 收藏

巴基斯坦猪DHRS4,SERPING1和APOR基因与死亡pH基因多态性的关系
摘要
Postmortem pH is a main factor influencing the meat quality in pigs. This study investigated the association of postmortem pH with single-nucleotide polymorphisms (SNPs) in the fourth member of the short-chain dehydrogenase/reductase family (DHRS4), the first member of serpin peptidase inhibitor, clade G (complement inhibitor) (SERPING1), and the apolipoprotein R precursor (APOR) genes in Berkshire pigs. The study included 437 pigs, and genotyping was conducted using the GoldenGate Assay (Illumina, San Diego, CA, USA). DHRS4, SERPING1, and APOR polymorphisms were significantly associated with pH45 or pH24 (p < 0.05). SERPING1 was also statistically significantly associated with water holding capacity (p < 0.05), which is closely associated with postmortem pH. These results suggest that SNPs in the DHRS4, SERPING1, and APOR genes have potential for use as genetic markers for the meat quality in pigs.
摘要译文
死亡的pH值是影响猪肉质量的主要因素。本研究在短链脱氢酶/还原酶家族(DHRS4)的第四个成员(丝氨酸蛋白酶抑制剂的第一个成员,进化枝G(补体抑制剂)(SERPING1))中研究了死后pH与单核苷酸多态性(SNP)和伯克希尔猪中的载脂蛋白R前体(APOR)基因。该研究包括437头猪,使用GoldenGate Assay(Illumina,San Diego,CA,USA)进行基因分型。 DHRS4,SERPING1和APOR多态性与pH 45或pH 24显着相关(p 0.05)。 SERPING1也与持水能力有统计学显着相关(p 0.05),这与死亡pH密切相关。这些结果表明,DHRS4,SERPING1和APOR基因中的SNP具有作为猪肉质量遗传标记的潜力。
Jung Hye Hwang[1];Sang Mi An[1];Seul Gi Kwon[1];Da Hye Park[1];Tae Wan Kim[2];Deok Gyung Kang[1];Go Eun Yu[1];Il-Suk Kim[2];Hwa Chun Park[3];Jeongim Ha[4];Chul Wook Kim[4]. Associations of the Polymorphisms in DHRS4, SERPING1, and APOR Genes with Postmortem pH in Berkshire Pigs[J]. Animal Biotechnology, 2017,28(4): 288-293