摘要
The therapeutic use of ionophores in veterinary medicine has grown in the last years, with resultant increase in the risk of poisoning in animals. Ionophores are used as food additives as coccidiostacts in several animal species and growth promoter and bloat prevention in ruminants. The most often used ionophores are monensin, lasalocid, narasin and salinomycin. There is a great variation in the susceptibility to the toxic effect of ionophores in different animal species. Poisoning can occur when the dosage is too high or when not correct doses for a certain animal species are given. Cases of poisoning have been described in sheep, swine, horses, dogs and poultry. For horses ionophores are extremely toxic. The use of ionophores is only safe when used accordingly to the instructions of the manufacturer and especially for each animal species. In this paper the most important data regarding clinical-pathological and pathogenic aspects, and also the conditions in which the poisoning may occur are critically reviewed.
摘要译文
的治疗用途在兽医离子载体的增长，在过去几年中，用在中毒的动物的风险因而增加。离子载体被用作食品添加剂在几个动物物种和生长促进剂和膨胀预防反刍动物coccidiostacts。最常用的离子载体莫能菌素，拉沙里菌素，甲基盐霉素和盐霉素。有一个在易感性离子载体在不同动物物种的毒性作用有很大的变化。中毒时可出现剂量过高或不正确剂量的某些动物物种给出时。中毒的情况下在羊，猪，马，狗和家禽已经描述。马离子载体剧毒。相应地用来制造商，尤其是对各动物物种中的说明，当使用离子载体是唯一安全。在本文中关于临床病理和致病方面最重要的数据，以及在其中可能发生中毒的条件是否严格审查。
NOGUEIRA, Vivian Assunção; FRANCA, Ticiana Nascimento ; PEIXOTO, Paulo Vargas. Ionophore poisoning in animals[J]. Pesquisa Veterinária Brasileira, 2009,29(3): 191-197