摘要
While certainly not a novel concept, faecal microbiota transplant (FMT) has recently garnered renewed interest in veterinary medicine due to its remarkable success in treating recurrent Clostridium difficile infection (CDI) in man. There is a dearth of information on indications and efficacy of FMT for the treatment of gastrointestinal disorders in the horse; however, based on evidence in man and other veterinary species, and anecdotal reports in horses, FMT may be a useful treatment for selected cases of acute and chronic diarrhoea and inflammatory bowel disease (IBD) in the horse. In the absence of evidence, expert opinion is offered on case selection and FMT procedure. More research is needed to explore the efficacy, indications and optimal preparation, storage and delivery of FMT to horses.
摘要译文
尽管粪便微生物群移植(FMT)当然不是一个新概念,但由于其在治疗人类复发性艰难梭菌感染(CDI)方面的显着成功,近来又重新引起了对兽医学的兴趣。缺乏有关FMT用于治疗马胃肠道病症的适应症和疗效的信息;然而,根据人类和其他兽医物种的证据以及马匹的轶事报道,FMT可能对马匹中的急性和慢性腹泻以及炎性肠病(IBD)的特定病例有用。在没有证据的情况下,就案例选择和FMT程序提供专家意见。需要更多的研究来探索FMT对马的功效,适应症和最佳制备,储存和递送。
K. R. Mullen[1];K. Yasuda[2];T. J. Divers[3];J. S. Weese[4];. Equine faecal microbiota transplant: Current knowledge, proposed guidelines and future directions[J]. Equine Veterinary Education, 2018,30(3): 151-160