摘要
A total of 120 Pekin ducks were distributed at random into four experimental groups, vaccinated or not against Newcastle disease (ND): G1 (Ulster 2C strain), G2 (B1 strain), G3 (LaSota strain), and G4 (nonvaccinated group). At 60 days of age, all groups were challenged with a pathogenic ND virus (NDV) suspension, and a group of specific pathogen free (SPF) chicks (G5) was also inoculated. Cloacal and tracheal swabs from all birds were collected after six, 14, 20, and 30 days post-challenge for virus isolation. NDV was isolated in 100% of SPF chicks. Pekin ducks from all groups, vaccinated or not, did not show any ND clinical signs, demonstrating that these birds are not susceptible to ND clinical disease. In the control group (G4), the virus was isolated 20 to 30 days after challenge, suggesting their possible NDV carrier state. In the vaccinated groups, no virus was isolated. This demonstrates that vaccination of white Pekin ducks against NDV is important to reduce NDV shedding in the field.
摘要译文
共有120北京鸭分布随机分为四个实验组，接种或不反对新城疫（ND）：G1（阿尔斯特2C株），G2（B1株），G3（LaSota毒株），和G4（未接种组）。在60日龄时，各组分别用致病ND病毒（NDV）的悬浮液的挑战，并有一批无特定病原体（SPF）的小鸡（G5）也进行接种。所有的鸟类泄殖腔和气管拭子采集后6，14，20，30天后的挑战进行病毒分离。 NDV分离的SPF鸡100％。从所有组北京鸭，接种或没有，没有表现出任何ND临床症状，这表明这些鸟不容易受到ND临床疾病。在对照组（G4），病毒分离挑战后20至30天，这表明其可能的NDV载波状态。在接种组，没有病毒被分离。这表明白色北京鸭抗NDV疫苗接种是重要的，以减少NDV脱落在外地。
NISHIZAWA, M. Newcastle disease in white Pekin ducks: response to experimental vaccination and challenge[J]. Revista Brasileira de Ciência Avícola, 2007,9(2): 123-125