摘要
During growth on surfaces, diverse microbial communities display topographies with captivating patterns. The quality and quantity of matrix excreted by resident cells play major roles in determining community architecture. Two current publications indicate that the cellular redox state and respiratory activity are important parameters affecting matrix output in the divergent bacteria Pseudomonas aeruginosa and Bacillus subtilis. These and related studies have identified regulatory proteins with the potential to respond to changes in redox state and respiratory electron transport and modulate the activity of the signal transduction pathways that control matrix production. These developments hint at the critical mechanistic links between environmental sensing and community behavior, and provide an exciting new context within which to interpret the molecular details of biofilm structure determination.
摘要译文
在表面上的增长，多样化的微生物群落显示地形与迷人的图案。在确定社区建筑的质量和矩阵的数量由固有细胞分泌起重要作用。两个电流的出版物表明细胞氧化还原状态和呼吸活动是影响在扩散菌绿脓杆菌和枯草杆菌矩阵输出的重要参数。这些和相关的研究已经确定调节蛋白与潜在响应的变化的氧化还原状态和呼吸电子传输和调制控制基质产生的信号转导途径的活性。这些事态发展暗示了环境感知和社会行为之间的关键环节机械，并提供在其中解释的生物膜结构测定的分子细节的令人兴奋的新环境。
Chinweike Okegbe; Alexa Price-Whelan; Lars EP Dietrich. Redox-driven regulation of microbial community morphogenesis[J]. Current Opinion in Microbiology, 2014,18: 39–45