摘要
Here we review key applications of separation technology in applied biology. We first sketch out the field as a whole, but then narrow our scope to the processing of fermentation products, particularly to high-value biologicals such as proteins and nucleotides. We go on to provide a qualitative overview describing the importance and general nature of this large field, major trends, and the strategies that have proven most fruitful in evolving effective separation and purification processes. We then give a detailed description of individual separations equipment and the principles governing their operation. We concentrate throughout on making the available literature accessible to the reader; we provide what is hoped to be a representative set of basic references. However, these references, in turn, include some that suggest promising new developments as well as a number of more specialized reviews. We hope that our overall result provides the reader with access to the most relevant literature. © 2004 Wiley Periodicals, Inc.
摘要译文
在这里，我们回顾分离技术的应用生物学的关键应用。我们首先绘制出了场作为一个整体，但我们缩小范围，以发酵产品的加工，特别是高价值的生物制品，如蛋白质和核苷酸。我们去提供一个定性的描述介绍这个大领域的重要性和一般性质，主要趋势，并已被证明最富有成果的不断发展有效的分离和纯化过程的策略。然后我们给个别分离设备的详细说明，并规范其运作的原则。我们专注于各地进行访问的读者现有的文献;我们提供什么样的希望是一组基本的参考代表。然而，这些参考文献，反过来，包括一些建议有前途的新发展，以及一些更专业的评论。我们希望我们的整体结果提供给读者获得最相关的文献。
E.N. Lightfoot and J.S. Moscariello. Bioseparations[J]. Biotechnology and Bioengineering, 2004,87(3): 259-273