摘要
Bacteriophages were initially considered to offer the key to the control of bacterial infections; early studies, however, proved largely unsuccessful. In the 1940s and 1950s, pioneering studies into the structure and physiology of host/phage interactions laid the basis for the development of molecular biology and a spectrum of new biotechnologically-based industries. Bacteriophages able to infect most procaryotic groups of organisms have been isolated, and are readily isolated from soil, water, and sewage and most environments colonised by bacteria. Ecologically, phages are as varied and as versatile as their hosts with some able to survive extremes of temperature (up to 95 °C) and extremes of pH as low as pH 1.
© 2001 Society of Chemical Industry
摘要译文
噬菌体最初认为提供的关键细菌感染的控制;早期的研究，然而，事实证明基本上不成功。在20世纪40年代和50年代，开拓性的研究到结构和主机/噬菌体相互作用生理学奠定了分子生物学的发展，新的生物技术为基础的工业的频谱。噬菌体能感染生物体的大多数原核生物组已被分离，并且容易从土壤，水和污水和大多数环境由细菌定植隔离。生态，噬菌体是一样各种各样并作为通用的它们与一些能主机生存极端温度（高达95
Richard Sharp[*]. Bacteriophages: biology and history[J]. Journal of Chemical Technology & Biotechnology, 2001,76(7): 667-672