期刊文献

Infection of Porcine Circovirus 2 (PCV2) in Intestinal Porcine Epithelial Cell Line (IPEC-J2) and Interaction between PCV2 and IPEC-J2 Microfilaments 收藏

猪圆环病毒2型（PCV2）的猪小肠上皮细胞（IPEC-J2）的PCV2和IPEC-J2微丝之间的感染与互动
原文求助 发布源
作者
Mengfei Yan [1] Liqi Zhu [1] Qian Yang [1]
作者单位
1. College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, PR China
关键词
PCV2 ;Intestinal epithelial cell ;Microfilaments
关键词译文
PCV2;肠上皮细胞;微丝
DOI
10.1186/s12985-014-0193-0
来源信息
Virology Journal ISSN：e1743-422X, 2014年, 11卷, 1期
摘要
Background Porcine circovirus-associated disease (PCVAD) is caused by a small pathogenic DNA virus, Porcine circovirus type 2 (PCV2), and is responsible for severe economic losses. PCV2-associated enteritis appears to be a distinct clinical manifestation of PCV2. Most studies of swine enteritis have been performed in animal infection models, but none have been conducted in vitro using cell lines of porcine intestinal origin. An in vitro system would be particularly useful for investigating microfilaments, which are likely to be involved in every stage of the viral lifecycle.
摘要译文
背景猪圆环病毒相关疾病（PCVAD）是由一个小致病DNA病毒，猪圆环病毒2型（PCV2）引起的，并且是负责严重经济lossesPCV2相关肠炎似乎是PCV2Most研究的不同的临床表现猪肠炎在动物感染模型已经进行，但没有已经在体外使用体外系统猪肠道originAn细胞系。将调查微丝，它们可能参与在病毒的每个阶段是特别有用的实施生命周期
Mengfei Yan [1] Liqi Zhu [1] Qian Yang [1]. Infection of Porcine Circovirus 2 (PCV2) in Intestinal Porcine Epithelial Cell Line (IPEC-J2) and Interaction between PCV2 and IPEC-J2 Microfilaments[J]. Virology Journal, 2014,11(1)