摘要
Purpose: Intrauterine insemination (IUI) is a method for the treatment of marital infertility involving the intrauterine or fallopian deposition of washed spermatozoa, depending on the amount of inseminated semen. In view of the divergent opinions about the inseminated volume, the objective of this study was to compare the two techniques (3.0 mL or 0.5 mL) in two groups of patients.
Methods: We performed 164 cycles of ovulation induction followed by IUI. The patients were divided into two groups according to the technique used. Group low volume – 50 cycles and 0.5 mL of inseminated semen; Group high volume – 114 cycles and 3.0 mL of inseminated semen. The cycle was monitored on the basis of endometrial thickness and follicular development measured by transvaginal ultrasound. Human chorionic gonadotrophin (hCG) was administered in the presence of a follicle measuring 18 mm in mean diameter. The procedure was performed after sperm washing using a discontinuous PureSperm® gradient, 40 h later.
Results: We obtained a similar clinical pregnancy rate for the two groups (14.0% for Group low volume and 15.7% for Group high volume). There was one abortion in each group. We detected no interference by any etiology of infertility or by the total motile recovered sperm with pregnancy rate.
Conclusions: The results did not demonstrate superiority of one method over the other, with both therapeutic alternatives being satisfactory for the treatment of infertile couples.
摘要译文
用途：宫腔内人工授精（IUI）是夫妻不孕不育的治疗累及宫腔内，或洗精子输卵管沉积的方法，取决于授精精液的量。鉴于对授精量不同意见，这项研究的目的是比较两种技术（3.0毫升或0。5毫升）在两组患者。方法：我们进行促排卵后IUI 164次。将患者根据所使用的技术，分为两组。集团低容量 - 50周期和0.5毫升精液人工授精的;集团高容量 - 114周期和3.0毫升精液人工授精的。该循环子宫内膜厚度和经阴道超声测量卵泡发育的基础上监测。人绒毛膜促性腺激素（HCG）施用在卵泡测量18毫米在平均直径的存在。采用不连续PureSperm精子洗涤之后进行的步骤0％的集团小批量和集团大批量15.7％）。有各组中的一个流产。我们没有检测到干扰不孕的病因的任何或全部恢复能动的精子受孕率。结论：结果并没有表现出一种方法的优于其他，既治疗方案是令人满意的不育夫妇治疗。
Vivian Ferreira do Amaral [1] Rui Alberto Ferriani [1] Rosana Maria dos Reis [1] Maria Matheus de Sala [1] Marcos Dias de Moura [1]. Andrology: Effect of Inseminated Volume on Intrauterine Insemination[J]. Journal of Assisted Reproduction and Genetics, 2001,18(8): 413-416