摘要
Benzophenone (BP-3) is an organic compound that is a common ingredient in lotions, conditioners, and other personal care products, which helps protect against ultraviolet radiation. This study investigated the effect of BP-3 on the structure of the integument and gills, as well as the activities of superoxide dismutase (SOD) and catalase (CAT) in the gills of Danio rerio. Fish were exposed to different concentrations (7, 70, and 700 μg L−1) of BP-3 for 7 and 14 d. For the histological analysis of the integument and gills, the fish were fixed in Bouin liquid and processed according to standard histologic procedures, and the tissue section slices were stained according to different histochemical methods. BP-3 caused tissue damage and morphological alterations in the gills; however, the integument showed no histological or morphological alterations. Furthermore, there was no observed correlation between the BP-3 concentration and exposure period and the gill alterations, as these did not occur in a linear manner. The gills were removed to evaluate the antioxidant defense; for this, CAT and SOD activities were measured, and a reduction of SOD activity was noted, whereas the CAT activity was not significantly affected.
摘要译文
苯甲酮（BP-3）是一种有机化合物，是乳液，护发素和其他个人护理产品中常见成分，有助于防止紫外线辐射。这项研究调查了BP-3对外皮和g的结构以及超氧化物歧化酶（SOD）和过氧化氢酶（CAT）在Danio rerio的gill中的影响。将鱼暴露于BP-3的不同浓度（7、70和700μgL -1 ）中，为7和14 d。为了对外膜和g的组织学分析，将鱼固定在布因液体中，并根据标准的组织学程序进行处理，并根据不同的组织化学方法对组织切片切片进行染色。BP-3在ill中引起组织损伤和形态改变；但是，外皮没有显示组织学或形态学改变。此外，BP-3浓度和暴露周期与g的改变之间没有观察到的相关性，因为它们没有以线性方式发生。将ill移除以评估抗氧化剂防御；为此，测量了CAT和SOD活性，并注意到SOD活性的降低，而CAT活性没有显着影响。
Jeffesson de Oliveira-Lima[1];Rafaela Luiza Dias da Cunha[2];Andrea Souza de Jesus Santana[2];Lycia de Brito-Gitirana[2]. Impact of benzophenone-3 on the integument and gills of zebrafish (Danio rerio)[J]. Journal of Environmental Science and Health, Part B, 2023,58(9): 603-615