摘要
Autism is a spectrum of conditions leading to challenges in speech, non-verbal communication, repetitive behaviour and social skills. Autism has many subtypes predominantly influenced by environmental and genetic factors. The development of autism is associated with sensitive sensory, gastrointestinal disorders, depression and sleep disorders. Autism predominantly affects children, of age 2 or 3, early diagnosis leads to potential outcomes. Children with autism are affected by gastrointestinal problems such as abdominal pain, constipation and diarrhoea. Microbial communities of the gut can influence many aspects of human physiology and gut-linked disorders. In addition, fermented foods consisting of probiotics have shown to reduce the impacts on neurology in humans. In this chapter, we will discuss the role of probiotics in combating autism. Further, the mode of action of gut microbes and their interaction with the disease to reverse the physiology, neurology and immunological disorders is discussed.
摘要译文
自闭症是一系列条件，导致言语，非口头沟通，重复行为和社交技能挑战。自闭症有许多主要受环境和遗传因素影响的亚型。自闭症的发展与敏感的感官，胃肠疾病，抑郁和睡眠障碍有关。自闭症主要影响2或3岁的儿童，早期诊断导致潜在的结果。自闭症的儿童受胃肠道问题的影响，如腹痛，便秘和腹泻。肠道的微生物群体可以影响人体生理学和肠道相关疾病的许多方面。此外，由益生菌组成的发酵食品已经显示出降低人类神经内科的影响。在本章中，我们将讨论益生菌在打击自闭症中的作用。此外，讨论了肠道微生物的作用方式及其与疾病的相互作用逆转生理学，神经学和免疫障碍。
Aravind Sundararaman.1;Kashika Sethi.2;Prakash Halami.1. Role of Probiotics in Autism Spectrum Disorders. Microbiome-Gut-Brain Axis[M].DE: Springer, 2022: 355-366