摘要
Synonyms
Affinity chromatographic materials; Chelating resins; Poly(N-isopropylacrylamide); Related topics: smart materials; Thermoresponsive polymers Definition
Bioseparation is separation of biological components for diagnostics and therapeutic purposes. Introduction
A term “bioseparation” is used to separate biological entity, for example, cells and proteins and other biologically active compounds available in our body, for diagnostics and/or therapeutic purposes. With a progress of recent biotechnologies, bioseparation technologies extend to separate genetically engineered proteins, nucleic acids, and even functional stem cells (embryonic stem (ES) cells, induced pluripotent stem (iPS) cells, and other somatostatic stem cells) for tissue engineering purposes. In this chapter, polymeric nanomaterials used in bioseparation purposes are summarized. Separation of Cells Using Polymeric Nanomaterials
More than 200 different types of cells are composed in our body. These cells have variety of bi ... This is an excerpt from the content Page %P Close Plain text Look
Inside Reference Work Entry Metrics Provided by Bookmetrix Reference tools Export citation Add to Papers Other actions About this Reference Work Reprints and Permissions ShareShare this content on Facebook Share this content on Twitter Share this content on LinkedIn Supplementary Material (0) References (13) References 1. Kataoka K, Kikuchi A (1993) Polymeric materials for cell separation, Chap 5.3. In: Tsuruta T, Hayashi T, Kataoka K, Ishihara K, Kimura Y (eds) Biomedical applications of polymeric materials. CRC, Boca Raton, p 345 2. Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P (2008) Molecular biology of the cells, 5th edn. Garland Science, New York, Chap 10 3. Schimpf M, Caldwell K, Calvin Giddings J (2000) Field-flow fractionation handbook. Wiley, New York, Chap 29 4. Janca J (1988) Field-flow fractionation. Dekker, New York, Chaps 1 and 6 5. Bigelow JC, Giddings JC, Nabeshima Y, Tsuruta T, Kataoka K, Okano T, Yui N, Sakurai Y (1989) Separation of B and T lymphocytes by a hybrid field-flow fractionation/adhesion chromatography technique. J Immunol Methods 117:289 6. Lundgren E (1997) Affinity separations of cells, Chap 8. In: Matejtschuk P (ed) Affinity separations, a practical approach. IRL Press, Oxford 7. Kikuchi A, Okano T (2005) Nanostructured designs of biomedical materials: applications of cell sheet engineering to functional regenerative tissues and organs. J Control Rel 101(1–3):69–84 8. Jungbauer A (2005) Chromatographic media for bioseparation. J Chromatogr A 1065:3–12 9. Mondal K, Gupta MN (2006) The affinity concept in bioseparation: evolving paradigms and expanding range of applications. Biomol Eng 23:59–76 10. Yoshizako K, Akiyama Y, Yamanaka H, Shinohara Y, Hasegawa Y, Carredano E, Kikuchi A, Okano T (2002) Regulation of protein binding toward a ligand on chromatographic matrixes by masking and forced-releasing effects using thermoresponsive polymer. Anal Chem 74(16):4160–4166 11. Yamanaka H, Yoshizako K, Akiyama Y, Sota H, Hasegawa Y, Shinohara Y, Kikuchi A, Okano T (2003) Affinity chromatography with collapsibly tethered ligands. Anal Chem 75(7):1658–1663 12. Ueda EKM, Gout PW, Morganti L (2003) Current and prospective applications of metal ion–protein binding. J Chromatogr A 988:1–23 13. Kikuchi A, Okano T (2002) Intelligent thermoresponsive polymeric stationary phases for aqueous chromatography for biological compounds. Prog Polym Sci 27:1165–1193 About this Reference Work Entry Title Bioseparation Reference Work Title Encyclopedia of Polymeric Nanomaterials Pages pp 206-209 Copyright 2015 DOI 10.1007/978-3-642-29648-2_229 Print ISBN 978-3-642-29647-5 Online ISBN 978-3-642-29648-2 Publisher Springer Berlin Heidelberg Copyright Holder Springer-Verlag Berlin Heidelberg Additional Links About this Reference Work Topics Polymer Sciences Nanotechnology Condensed Matter Physics Nanochemistry Industry Sectors Pharma Materials & Steel Automotive Chemical Manufacturing Biotechnology Consumer Packaged Goods Aerospace Oil, Gas & Geosciences Engineering eBook Packages eBook Package english full Collection eBook Package english Chemistry & Material Science Editors Shiro Kobayashi (1) Klaus Müllen (2) Editor Affiliations 1. Center for Fiber and Textile Science, Kyoto Institute of Technology 2. Max Planck Institute for Polymer Research Authors Akihiko Kikuchi (227) Author Affiliations 227. Department of Materials Science and Technology, Tokyo University of Science, 6-3-1 Niijuku, Katsushika, Tokyo, 125-8585, Japan Continue reading...
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