摘要
Although the scientific evidence has shown that the aging process may affect the composition and metabolic activity of human intestinal microbiota and its interaction with the immune system, this relationship still requires a better understanding. Probiotics, prebiotics, and synbiotics have shown the potential to alleviate common gastrointestinal problems in elderly people by modulating microbial activity and immune status. In spite of the promising results, more intervention trials with probiotics and/or prebiotics are needed to elucidate the mechanisms of action involved and to undoubtedly demonstrate their effectiveness in aged people. The aim of this chapter is to focus on the gut microbial changes associated with aging and the potential benefits of pro-, pre-, and synbiotics to modulate the intestinal microbiota and to contribute for the maintenance of the health and well-being in the elderly.
摘要译文
尽管科学证据表明，老化过程可能会影响该组合物和人类肠道菌群的代谢活性和其与免疫系统相互作用，这关系仍然需要更好understandingProbiotics，益生元，以及合生元已经表明，以缓解常见的潜在通过调节微生物活性和免疫statusIn尽管有希望的结果的，与益生菌和/或益生元以上干预试验老年人肠胃病需要阐明参与作用机制并无疑证明其在老年peopleThe目的有效性本章是把重点放在与老龄化相关的肠道微生物的变化和亲的潜在好处，前，合生元和调节肠道微生物，是维护健康和中老年人的福祉作出贡献
Raquel Bedani * , Susana Marta Isay Saad * , Katia Sivieri †. Chapter 37 – Potential Benefits of Probiotics, Prebiotics, and Synbiotics on the Intestinal Microbiota of the Elderly. Probiotics, Prebiotics, and Synbiotics[M].NL: Elsevier, 2016: 525-538