摘要
This chapter offers a comprehensive approach to equine laboratory diagnostics, including hematology, clinical chemistry, serology, body fluid analysis, microbiology, clinical parasitology, endocrinology, immunology, and molecular diagnostics for systemic infection caused by Leptospira. One of the most challenging diagnostic dilemmas in equine infectious disease is determining how to interpret clinical signs, history, and laboratory test results for horses suspected of having leptospirosis. The most commonly reported equine manifestations of equine leptospirosis are abortion and equine recurring uveitis (ERU). Results of routine diagnostic tests are nonspecific and reflect infection, inflammation, and possibly organ failure, including leukocytosis with neutrophilia, indicators of liver and kidney disease, occasionally hyperbilirubinemia and hyperfibrinogenemia, and isosthenuria on urinalysis. Leptospirosis is a zoonotic disease shed in the urine of a diversity of domestic animals and wildlife, thus a case in one horse suggests risk to other animals in the same area, including possibly humans.
摘要译文
本章提供了马实验室诊断的综合方法，包括血液学，临床化学，血清学，体液分析，微生物学，临床寄生虫学，内分泌学，免疫学以及由钩端螺旋体引起的全身感染的分子诊断。马传染病中最具挑战性的诊断困境之一是确定如何解释临床体征，病史，以及怀疑患有钩端螺旋体病的马的实验室测试结果。马钩端螺旋体病最常见的马表现是流产和马复发性葡萄膜炎（ERU）。常规诊断试验的结果是非特异性的，反映了感染，炎症和可能的器官衰竭，包括白细胞增多伴中性粒细胞增多，肝脏和肾脏疾病指标，偶尔会发生高胆红素血症和高纤维蛋白原血症以及尿液分析中的等静尿尿。钩端螺旋体病是多种家畜和野生动物的尿液中流行的人畜共患病，因此一匹马的情况表明对同一地区的其他动物（包括可能的人）有风险。
Janet Foley[1];Mary H. Straub[1]. Leptospira spp.. Interpretation of Equine Laboratory Diagnostics[M].US: Wiley, 2017: 203-207