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Introduction to the Baculoviruses 收藏

杆状病毒介绍
摘要
Of all the viruses known to mankind, baculoviruses are the most beneficial from an anthropocentric viewpoint. While other viruses are studied because they cause problems, the basis of modern baculovirology was stimulated by the potential utility of baculoviruses to control insect pests (see Chapter 13, this volume). The current use of baculoviruses as gene expression vectors (see Chapter 14) evolved from the molecular biology of baculoviruses, a research area pursued while assessing the safety and improving the efficacy of baculovirus pesticides. Basic molecular studies also led to the use of baculoviruses and their genes to explore fundamental questions in biology such as the nature and function of apoptotic pathways (see Chapter 10). However, baculoviruses also cause disease in beneficial species, not just pest species, and understanding what controls the host range of these viruses (see Chapter 9) will become even more important if a balanced ecological perspective displaces anthropocentrism.
摘要译文
在人类已知的所有病毒中,杆状病毒是以人类中心观点最有利的。虽然其他病毒因为引起问题而被研究,杆状病毒控制害虫的潜在效用刺激了现代杆状病毒学的基础(见本书第13章)。目前将杆状病毒用作基因表达载体(参见第14章)是从杆状病毒的分子生物学进化而来的,在评估杆状病毒农药的安全性和提高效力的同时追求研究领域。基础分子研究也导致使用杆状病毒及其基因来探索生物学中的基本问题,如凋亡途径的性质和功能(参见第10章)。然而,杆状病毒也在有益物种中引起疾病​​,不仅仅是害虫物种,如果平衡的生态学视角取代了人类中心主义,那么理解控制这些病毒的宿主范围(见第9章)的东西将变得更加重要。
Lois K. Miller1. Introduction to the Baculoviruses. The Baculoviruses[M].DE: Springer, 1997: 1-6