摘要
Ingestion of carotenoids from foods can vary remarkably and is dependent on numerous factors, such as the composition of the food in question. What is valid for foods also holds true for carotenoid forms offered for addition to foods, beverages and nutritional supplements. Successful commercialization of carotenoids depends on appropriate forms being tailored to their intended use. The fortification of many foods and nutritional supplements requires water-dispersible delivery systems such as emulsions, micelles or hydro-colloidal suspensions. This chapter discusses in detail the various formulation technologies available. Major forms marketed nowadays are oily suspensions, oil-in-water emulsions and water-dispersible powders. Nutritional supplements contain micronutrients in dense concentrations and therefore require high-potency forms. The extent to which the composition of the form has a crucial influence on bioavailability is not easy to judge, since in many cases the formulation excipients and applied technologies are linked. Nevertheless, the fact that forms comprising the same potency of carotenoid can vary dramatically in bioavailability has been proven once more.
摘要译文
从食物中摄入类胡萝卜素可能有显着差异,并取决于许多因素,例如所讨论食物的组成。什么是有效的食物也适用于类胡萝卜素形式提供添加到食品,饮料和营养补充剂。类胡萝卜素的成功商业化取决于适合其预期用途的适当形式。许多食品和营养补充剂的强化需要水分散性递送系统,如乳液,胶束或水胶体悬浮液。本章详细讨论了可用的各种配方技术。目前销售的主要形式是油性悬浮液,水包油乳液和水分散性粉末。营养补充剂含有浓度较高的微量营养素,因此需要高效的形式。形式的组成对生物利用度的重要影响的程度不容易判断,因为在许多情况下制剂赋形剂和应用技术是相互关联的。尽管如此,包含类胡萝卜素相同效力的形式在生物利用度方面可以显着变化的事实已经被再次证明。
Loni Schweikert1. The Bioavailability of Carotenoid Forms. Sustainable Nutrition in a Changing World[M].DE: Springer, 2017: 289-294