期刊文献

In Vitro Evaluation of Antimicrobial Effect of Phytobiotics Mixture on Salmonella spp. Isolated from Chicken Broiler 收藏

植物生物混合物对沙门氏菌属的抗菌作用的体外评估。从鸡肉肉鸡中孤立

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作者

Hubert Iwiński;Karolina Wódz;Karolina Chodkowska;Tomasz Nowak;Henryk Różański

作者单位

[1] Department of Chemistry, the Faculty of Food Science, Wrocław University of Environmental and Life Sciences, C.K. Norwida 25, 50-375 Wrocław, Poland [2] AdiFeed Sp. z o.o., Opaczewska, 02-201 Warszawa, Poland [3] Laboratory of Molecular Biology, Vet-Lab Brudzew, Turkowska 58c, 62-720 Brudzew, Poland [4] Krzyżanowski Partners Spółka z o.o., Zakładowa 7, 26-670 Pionki, Poland [5] Laboratory of Industrial and Experimental Biology, Institute for Health and Economics, Carpathian State College in Krosno, Rynek 1, 38-400 Krosno, Poland [*] Author to whom correspondence should be addressed. Academic Editors: Marc Maresca, Anahì Bucchini and Laura Giamperi Antibiotics 2022, 11(7), 868; https://doi.org/10.3390/antibiotics11070868

关键词

Salmonella Typhimurium; Salmonella Enteritidis; phytobiotics; antimicrobial resistance; MIC; chicken broiler; resistance genes; thymol; 1,8-cineole

关键词译文

沙门氏菌鼠伤寒；沙门氏菌Enteritidis;植物生物学；抗菌耐药性；麦克风鸡肉烤；抗性基因；百里香1,8-Cineole

发布日期

2022-06-28

页码

868

DOI

10.3390/antibiotics11070868

来源信息

Antibiotics ISSN：2079-6382, 2022年, 11卷, 7期, 868页

摘要

Background: The identification of natural antibacterial agents from various sources that can act effectively against disease-causing foodborne bacteria is one of the major concerns throughout the world. In the present study, a unique phytobiotics mixture containing thymol, menthol, linalool, trans-anethole, methyl salicylate, 1,8-cineole, and p-cymene was evaluated for antibacterial activity against selected strains of Salmonella spp. Results: The phytobiotics mixture was effective against Salmonella enterica subsp. enterica serovars Enteritidis, Typhimurium, and Kentucky. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of this unique mixture for these three pathogens were 1:256. Among these three strains, one S. Kentucky presented the most extensive resistance profiles to 18 antibiotics belonging to 5 classes of antibiotics. One of S. Typhimurium presents extensive resistance profiles to 14 antibiotics belonging to 5 classes of antibiotics. Conclusions: The results suggest that the phytobiotics mixture used in the experiment can be used as a strong natural antibacterial agent against Gram-negative foodborne pathogens such as S. Typhimurium, S. Kentucky, and S. Enteritidis. This is a preliminary analysis of the effectiveness of a phytobiotic product in an in vitro model, which may be the starting point for further studies, including in vivo animal models.

摘要译文

背景：从各种来源的天然抗菌剂鉴定可以有效地针对引起疾病的食物生殖的细菌，这是全世界的主要关注点之一。在本研究中，评估了含有百里香，薄荷醇，linalool，跨 - 氨基甲酯，水杨酸甲酯，1,8-甲烷和P-甲烯的独特植物生物学混合物的抗菌活性，以抗细菌活性。结果：植物生物的混合物对肠沙门氏菌亚种有效。 Enterica血清Enteritidis，Typhimurium和Kentucky。这三种病原体的这种独特混合物的最小抑制浓度（MIC）和最小杀菌浓度（MBC）值为1：256。在这三种菌株中，一位肯塔基州呈现了属于5种抗生素的18种抗生素的最广泛的耐药性。鼠伤寒链球菌之一呈现出属于5种抗生素的14种抗生素的广泛耐药性。结论：结果表明，实验中使用的植物生物混合物可以用作针对革兰氏阴性食源性病原体（如Typhimurium，S。Kentucky和Enteritidis）的强大天然抗菌剂。这是对体外模型中植物生物产物的有效性的初步分析，这可能是进一步研究的起点，包括体内动物模型。

Hubert Iwiński;Karolina Wódz;Karolina Chodkowska;Tomasz Nowak;Henryk Różański. In Vitro Evaluation of Antimicrobial Effect of Phytobiotics Mixture on Salmonella spp. Isolated from Chicken Broiler[J]. Antibiotics, 2022,11(7): 868