摘要
Zoonotic leishmaniosis due to Leishmania infantum is a vector-borne disease endemic in southern Europe and dogs are the main reservoir for this infection. Seasonal variations in antibody titers in this species in areas where phlebotomine vectors have seasonal patterns of activity are important for epidemiological, preventive and clinical studies related with canine leishmaniosis. It has been suggested that cats, rabbits and ferrets may act as peridomestic reservoirs and not only as accidental hosts. The aim of this study was to determine if seropositive ferrets (Mustela putorius furo) to Leishmania could be affected by seasonal variations of anti-Leishmania antibodies. A group of seropositive clinically healthy ferrets (n = 21) were included in this study. A significant reduction in anti-Leishmania infantum antibodies was detected during non-transmission period (December 2020-February 2021) in comparison to transmission period (April-October 2020). This study describes for the first time a seasonal variation in the anti-Leishmania antibodies detected in domestic ferrets following natural exposure during sand fly transmission period and the following non-sand fly transmission period in a Mediterranean area considered as an area where L. infantum is endemic.
摘要译文
由于Leishmania Infantum因南欧南欧的流域而引起的，狗是这种感染的主要水库因这种感染的主要水库。这种物种中抗体滴度的季节变异在斑botomine载体的季节性活动模式中对于流行病学，预防和临床研究是重要的，与犬利伊氏病有关。有人建议，猫，兔子和雪貂可以充当白云母的储层，不仅是偶然的主持人。本研究的目的是确定血清阳性雪貂（Mustela Putorius Furo）是否可能受到抗LeishMania抗体的季节性变化的影响。本研究包括一组血清阳性临床健康的雪貂（N = 21）。与传输期间（4月20日4月至1020年）相比，在非传输期间（2020年12月）（2020年12月）期间检测到抗LeishMania幼儿抗体的显着减少。本研究描述了在砂飞传输期间自然暴露后在国内雪貂中检测到的抗Leishmania抗体的季节变异，并且在被认为是L. Infantum的地区的地中海区域中的以下非砂飞传输时期地方性。
JacoboGiner[a][b][d];MaiteVerde[a][b][c];AndrésYzuel[b];HéctorRuiz[a];DeliaLacasta[a][c];CristinaRiera[e];RoserFisa[e];María MagdalenaAlcover[e];AntonioFernández[a][b][c]. Antibodies to Leishmania in naturally exposed domestic ferrets (Mustela putorius furo) in Spain[J]. Veterinary Parasitology, 2021,296