摘要
Food ingredients have shown beneficial effect in delaying aging and extend lifespan. There are Chinese herbal medicines in the category of “homology of medicine and food”. In order to find out whether these herbal medicines can act as food component to slow aging, this study selected 12 Chinese herbal medicines containing strong antioxidant components, Canarium album, Amomum villosum, Elsholtzia splendens, Foeniculum vulgare, Fructus hordei germinatus, stir-baked Fructus hordei germinatus, Lilium brownie, Citrus medica, Sophora japonica, Myristica fragrans, Herba houttuyniae, Carthamus tinctoriu, and examined the effects on lifespan using Drosophila melanogaster as the model organism. Our results show that the extracts of the 12 Chinese herbal medicines have various effects on longevity. Some reduced the lifespan in both sexes. Some only shortened the lifespan in one sex. Some have no significant effect in both sexes. There are two herbal medicine extended lifespan, but only in females. The present results suggest that herbal medicines may provide potential candidates for anti-aging ingredients.
摘要译文
食品成分表明延迟老化并延长寿命的有益效果。中草药在“医学与食品同源性”类中。为了了解这些草药是否可以作为食品组分减缓衰老，本研究选择了12种中草药，含有强抗氧化成分，Canarium专辑，Amomum villosum，elsholtzia splendens，Foeniculum vulgare，Fructus hordei germinatus，搅拌烤面包HORDEI GERMINATUS，椴树，柑橘MEDICA，Sophora Japonica，Myristica Fragrans，Herba Houtuyniae，Carthamus Tinctoriu，以及使用果蝇Melanogaster作为模型生物的寿命效果。我们的研究结果表明，12中草药的提取物对寿命有各种影响。一些减少了两性的寿命。有些人只缩短了一个性别的寿命。有些人对两性没有显着影响。有两种草药延伸的寿命，但只有女性。本结果表明草药可以为抗衰老成分提供潜在的候选物。
Honglin Li[a];Boying Liang[a];Yue Cao[b];Yifan Xu[a];Jiale Chen[a];Yixin Yao[a];Jie Shen[a];Danyu Yao[a]. Effects of Chinese herbal medicines on lifespan in Drosophila[J]. Experimental Gerontology, 2021,154