摘要
Plants produce polyphenols, which are considered highly essential functional foods in our diet. They are classified into several groups according to their diverse chemical structures. Flavanoids, lignans, stilbenes, and phenolic acids are the four main families of polyphenols. Several in vivo and in vitro research have been conducted so far to evaluate their health consequences. Polyphenols serve a vital function in the protection of the organism from external stimuli and in eliminating reactive oxygen species (ROS), which are instigators of several illnesses. Polyphenols are present in tea, chocolate, fruits, and vegetables with the potential to positively influence human health. For instance, cocoa flavan-3-ols have been associated with a decreased risk of myocardial infarction, stroke, and diabetes. Polyphenols in the diet also help to improve lipid profiles, blood pressure, insulin resistance, and systemic inflammation. Quercetin, a flavonoid, and resveratrol, a stilbene, have been linked to improved cardiovascular health. Dietary polyphenols potential to elicit therapeutic effects might be attributed, at least in part, to a bidirectional association with the gut microbiome. This is because polyphenols are known to affect the gut microbiome composition in ways that lead to better human health. Specifically, the gut microbiome converts polyphenols into bioactive compounds that have therapeutic effects. In this review, the antioxidant, cytotoxicity, anti-inflammatory, antihypertensive, and anti-diabetic actions of polyphenols are described based on findings from in vivo and in vitro experimental trials.
摘要译文
植物产生多酚，在我们的饮食中被认为是高度必不可少的功能性食品。它们根据各种化学结构分为几组。类黄酮，木脂蛋白，口号和酚酸是多酚的四个主要家族。到目前为止，已经进行了几项体内和体外研究，以评估其健康后果。多酚在保护生物免受外部刺激和消除活性氧（ROS）的保护方面起着至关重要的作用，这些氧气是几种疾病的刺激者。多酚存在于茶，巧克力，水果和蔬菜中，有可能积极影响人类健康。例如，可可黄合3-醇与心肌梗塞，中风和糖尿病的风险降低有关。饮食中的多酚还有助于改善脂质谱，血压，胰岛素抵抗和全身性炎症。槲皮素，类黄酮和白藜芦醇（一种石碑）与改善心血管健康有关。饮食中多酚可能引起治疗作用的潜力至少部分地归因于与肠道微生物组的双向关联。这是因为已知多酚以导致改善人类健康的方式影响肠道微生物组的组成。具体而言，肠道微生物组将多酚转化为具有治疗作用的生物活性化合物。在这篇综述中，基于体内和体外实验试验的发现，描述了多酚的抗氧化剂，细胞毒性，抗炎，抗高血压和抗糖尿病作用。
Ananya Rana[1];Mrinal Samtiya[2];Tejpal Dhewa[2];Vijendra Mishra[1];Rotimi E. Aluko[3]. Health benefits of polyphenols: A concise review[J]. Journal of Food Biochemistry, 2022,46(10)