期刊文献

Clinical leishmaniosis in a domestic ferret (Mustela putorius furo) treated with miltefosine plus allopurinol: Serological and clinical follow-up 收藏

在国内雪貂（Mustela Putorius Furo）的临床leishmaniosis用Miltefosine Plus Allopurinol治疗：血清学和临床随访

原文求助发布源

作者

Jacobo Giner[a][b][c];Sergio Villanueva-Saz[b][c][d];María Magdalena Alcover[e];Cristina Riera[e];Roser Fisa[e];Maite Verde[b][c][d];Antonio Fernández[b][c][d];Andrés Yzuel[c]

作者单位

[a]aMenescalia Veterinary Clinic, Ismael Merlo Actor, 5, 46020, Valencia, SpainMenescalia Veterinary Clinic, Ismael Merlo Actor, 5, 46020 Valencia, Spain[b]bAnimal Pathology Department, Veterinary Faculty, University of Zaragoza, Miguel Servet 177, 50013 Zaragoza, SpainAnimal Pathology Department, Veterinary Faculty, University of Zaragoza, Miguel Servet 177, 50013 Zaragoza, Spain[c]cClinical Immunology Laboratory, Veterinary Faculty, University of Zaragoza, Miguel Servet 177, 50013 Zaragoza, SpainClinical Immunology Laboratory, Veterinary Faculty, University of Zaragoza, Miguel Servet 177, 50013 Zaragoza, Spain[d]dInstituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), Zaragoza, SpainInstituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA)[e]eLaboratory of Parasitology, Pharmacy Faculty, University of Barcelona, Avda. Joan XXIII s/n, 08028 Barcelona, SpainLaboratory of Parasitology, Pharmacy Faculty, University of Barcelona, Avda. Joan XXIII s/n, 08028 Barcelona, Spain

关键词

Dermatitis;Ferret;Leishmania infantum;Leishmaniosis;Mustela putorius furo;

关键词译文

皮炎;雪貂; Leishmania Infantum; Leishmaniosis; Mustela Putorius Furo;

发布日期

1 July 2021

DOI

10.1016/j.vprsr.2021.100607

来源信息

Veterinary Parasitology: Regional Studies and Reports ISSN：2405-9390, 2021年, 25卷

摘要

The published information on the treatment of mustelid leishmaniosis is extremely scarce because there are only two case reports available. In one case, a domestic ferret (Mustela putorius furo) was treated with a combination of meglumine antimoniate plus allopurinol and, in the other case, a therapeutic regimen with allopurinol was administrated to a Eurasian otter (Lutra lutra). This article describes for the first time a combined therapeutic protocol with miltefosine (2 mg/kg once a day during 28 days per os), and allopurinol (10 mg/kg twice a day PO sine die) in a domestic ferret with splenomegaly, lymphadenomegaly and a facial pyogranulomatous dermatitis, with a moderate level of antibodies to Leishmania infantum.

摘要译文

有关甘蔗德利氏菌类治疗的公布信息极为稀缺，因为只有两种报告提供。在一个案例中，用Meglumine Antimoniate Plus Allopurinol的组合治疗了国内雪貂（Mustela Putorius Furo），在另一个情况下，将治疗方案与Allopurinol施用到欧亚水獭（Lutra Lutra）。本文介绍了第一次与Miltefosine的组合治疗方案（每次28天的每天28天的每天2mg / kg），以及在带有脾肿大的家用雪貂中的Allopurinol（每天每天两次Po Sine Die），淋巴结肿大和面部肌肉细菌性皮炎，对Leishmania Infantum的适度抗体。

Jacobo Giner[a][b][c];Sergio Villanueva-Saz[b][c][d];María Magdalena Alcover[e];Cristina Riera[e];Roser Fisa[e];Maite Verde[b][c][d];Antonio Fernández[b][c][d];Andrés Yzuel[c]. Clinical leishmaniosis in a domestic ferret (Mustela putorius furo) treated with miltefosine plus allopurinol: Serological and clinical follow-up[J]. Veterinary Parasitology: Regional Studies and Reports, 2021,25