摘要
One of the challenges in understanding chemical evolution is the large number of starting organics and environments that were plausible on early Earth. Starting with realistic organic mixtures and using chemical analyses that are not biologically biased, understanding the interplay between organic composition and environment can be approached using statistical analysis. In this work, a mixture of 73 organics was cycled through dehydrating conditions five times, considering environmental parameters of pH, salinity, and rehydration solution. Products were analyzed by HPLC, amide and ester assays, and phosphatase and esterase assays. While all environmental factors were found to influence chemical evolution, salinity was found to play a large role in the evolution of these mixtures, with samples diverging at very high sea salt concentrations. This framework should be expanded and formalized to improve our understanding of abiogenesis.
摘要译文
理解化学演化的挑战之一是在地球早期合理的大量起始有机物和环境。从逼真的有机混合物开始，并使用没有生物学上有偏见的化学分析开始，可以使用统计分析来了解有机成分和环境之间的相互作用。在这项工作中，考虑到pH，盐度和再合化溶液的环境参数，将73种有机物的混合物通过脱水条件进行了循环。通过HPLC，酰胺和酯测定以及磷酸酶和酯酶测定法分析产物。虽然发现所有环境因素都会影响化学进化，但发现盐度在这些混合物的演化中起着很大的作用，样品在非常高的海盐浓度下发散。该框架应扩展和形式化，以提高我们对生物发生的理解。
Kiernan Foster;Brooke Hillman;Vahab Rajaei;Kimsorn Seng;Sarah Maurer. Evolution of Realistic Organic Mixtures for the Origins of Life through Wet–Dry Cycling[J]. Sci, 2022,4(2): 22